Evidence map›Paper›PMID 39315802›Full record

ArticlemBio2024

Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis.

Valerio Secli, Emma Michetti, Francesca Pacello, Federico Iacovelli, Mattia Falconi, Maria Luisa Astolfi, Daniela Visaggio, Paolo Visca, Serena Ammendola, Andrea Battistoni

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Identification of iron and zinc responsive TonB-dependent transporters in Pseudomonas aeruginosa.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Review
  3. Cobalt mitigates zinc-starvation effects in Pseudomonas aeruginosa.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  4. Pseudopaline-mediated zinc uptake byInfection and immunity · 2026
    Article
  5. Deletion ofApplied and environmental microbiology · 2026
    Article
  6. Article
  7. Proteomic profiling of zinc homeostasis mechanisms inbioRxiv : the preprint server for biology · 2025
    Article
  8. Modelling host-pathogen interactions:Microbiology (Reading, England) · 2025
    Article
  9. Relationship between Pyochelin andInternational journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Valerio SecliDepartment of Biology, Tor Vergata University of Rome, Rome, Italy.
Emma MichettiDepartment of Biology, Tor Vergata University of Rome, Rome, Italy.
Francesca PacelloDepartment of Biology, Tor Vergata University of Rome, Rome, Italy.
Federico IacovelliDepartment of Biology, Tor Vergata University of Rome, Rome, Italy.
Mattia FalconiDepartment of Biology, Tor Vergata University of Rome, Rome, Italy.
Maria Luisa AstolfiDepartment of Chemistry, Sapienza University of Rome, Rome, Italy.
Daniela VisaggioDepartment of Science, Roma Tre University, Rome, Italy.
Paolo ViscaDepartment of Science, Roma Tre University, Rome, Italy.ORCID 0000-0002-6128-7039
Serena AmmendolaDepartment of Biology, Tor Vergata University of Rome, Rome, Italy.ORCID 0000-0003-1436-0608
Andrea BattistoniDepartment of Biology, Tor Vergata University of Rome, Rome, Italy.ORCID 0000-0003-4085-7917

Funding

Cystic Fibrosis Foundation (CFF) BATTIS19IOMUR Prin 2022 - founded by the European Community - Next Generation EU 2022E57Z3KRome Technopole, NRP Mission 4, Component 2, Investment 1.5, founded by the European Community Next Generation Eu ECS 0000024
6 · The paper itself

Abstract

Limiting the availability of transition metals at infection sites serves as a critical defense mechanism employed by the innate immune system to combat microbial infections. IMPORTANCE: The mechanisms underlying the remarkable ability of

Indexed as

Bacterial ProteinsHomeostasisPhenolsPseudomonas aeruginosaThiazolesZincBiological TransportCobaltGene Expression Regulation, BacterialOperonRepressor ProteinsBacterial ProteinsCobaltPhenolspyochelinRepressor ProteinsThiazolesZinccystic fibrosisiron transportmetallophoremetal transportPseudomonas aeruginosasiderophoreszincophoreszinc transport

Identifiers

PMID39315802
PMCPMC11481552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.