ArticleContact dermatitis2025
The association between wet work and hand eczema in the Dutch general population: Application of a job exposure matrix to the lifelines cohort study.
Article in Contact dermatitis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Post-Occlusion Application of Skin Protective Creams Does Not Affect Occlusion-Induced Barrier Changes: A Randomized Controlled Experimental Study.Contact dermatitis · 2026Trial
- Challenges of using the Occupational Asthma-specific job exposure matrix to assess occupational exposure and hand eczema.Frontiers in allergy · 2026Article
- The association between wet work and hand eczema in the Dutch general population: Application of a job exposure matrix to the lifelines cohort study.Contact dermatitis · 2025Article
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Authors and funding
6 authors.
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Abstract
backgroundStudies on wet work and hand eczema (HE) frequently rely solely on self-reports regarding wet work.
objectivesTo assess the association between wet work and moderate-to-very-severe HE, within the Dutch general population, by using a (sex-specific) job exposure matrix (JEM).
methodsWithin the Lifelines Cohort Study, participants with self-reported moderate-to-very-severe HE at worst in the past year were linked to data from the Danish (sex-specific) wet work JEM, a tool that links occupations with wet work indices (including duration and probability of glove use, wet hands and total wet work for at least 2 and 4 h/working day).
resultsIn total, 56 978 (41.9%) participants were included. The multivariate binary logistic regression analyses showed significant associations between all facets of wet work and moderate-to-very-severe HE. When using the sex-specific JEM, significant associations were found in females, but not in males.
conclusionsThis study is the first to use a wet work-specific JEM in a general population sample, and found positive associations between wet work and HE. The sex-specific findings should be interpreted with caution, due to limitations inherent in using a JEM, and should be further explored with observational studies, with a focus on duration, frequency, and exposure type.
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