Evidence map›Paper›PMID 39315312›Full record

ReviewFrontiers in bioengineering and biotechnology2024

Alternatives of mesenchymal stem cell-derived exosomes as potential therapeutic platforms.

Sihun Lee, Se Young Jung, Donghyeon Yoo, Dabin Go, Ji Yeong Park, Jong Min Lee, Wooram Um

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sihun Lee *Department of Biotechnology, College of Fisheries Science, Pukyong National University, Busan, Republic of Korea.
Se Young Jung *Department of Biotechnology, College of Fisheries Science, Pukyong National University, Busan, Republic of Korea.
Donghyeon YooDepartment of Biotechnology, College of Fisheries Science, Pukyong National University, Busan, Republic of Korea.
Dabin GoDepartment of Biotechnology, College of Fisheries Science, Pukyong National University, Busan, Republic of Korea.
Ji Yeong ParkDepartment of Biotechnology, College of Fisheries Science, Pukyong National University, Busan, Republic of Korea.
Jong Min LeeDepartment of Biotechnology, College of Fisheries Science, Pukyong National University, Busan, Republic of Korea.
Wooram UmDepartment of Biotechnology, College of Fisheries Science, Pukyong National University, Busan, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With outstanding therapeutic potential in the tissue regeneration and anti-inflammation, mesenchymal stem cell-derived exosomes (MSC-EXOs) have emerged as a prominent therapeutic in recent. However, poor production yield and reproducibility have remained as significant challenges of their practical applications. To surmount these challenges, various alternative materials with stem cell-like functions, have been recently investigated, however, there has been no comprehensive analysis in these alternatives so far. Here, we discuss the recent progress of alternatives of MSC-EXOs, including exosomes and exosome-like nanovesicles from various biological sources such as plants, milk, microbes, and body fluids. Moreover, we extensively compare each alternative by summarizing their unique functions and mode of actions to suggest the expected therapeutic target and future directions for developing alternatives for MSC-EXOs.

Indexed as

exosomesextracellular vesiclesmembrane vesiclesnanovesiclesregenerative medicine

Identifiers

PMID39315312
PMCPMC11417005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.