Evidence map›Paper›PMID 39315202›Full record

ArticleHeliyon2024

Clinical sequencing reveals diagnostic, therapeutic, and prognostic biomarkers for adult-type diffuse gliomas.

Zhenyan Li, Zhenghao Deng, Fangkun Liu, Chuntao Li, Kui Yang, Xuan Gong, Songshan Feng, Yu Zeng, Hongshu Zhou, Fan Fan and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Genomic Profiling in Glioma Patients to Explore Clinically Relevant Markers.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhenyan LiDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Zhenghao DengDepartment of Pathology, Xiangya Hospital Central South University, Changsha, 410008, China.
Fangkun LiuDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Chuntao LiDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Kui YangDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Xuan GongDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Songshan FengDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Yu ZengDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Hongshu ZhouDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Fan FanDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Chengke LuoDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Zhixiong LiuDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.
Mingyu ZhangDepartment of Neurosurgery, Xiangya Hospital Central South University, Changsha, 410008, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse gliomas in adults are highly infiltrative and largely incurable. Whole exome sequencing (WES) has been demonstrated very useful in genetic analysis. Here WES was performed to characterize genomic landscape of adult-type diffuse gliomas to discover the diagnostic, therapeutic and prognostic biomarkers. Somatic and germline variants of 66 patients with adult-type diffuse gliomas were detected by WES based on the next-generation sequencing. TCGA and CGGA datasets were included to analyze the integrated diagnosis and prognosis. Among 66 patients, the diagnosis of 9 cases was changed, in which 8 cases of astrocytoma were corrected into

Indexed as

Diffuse gliomaGenomic profilingPrognostic biomarkerWhole exome sequencing

Identifiers

PMID39315202
PMCPMC11417559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.