Evidence map›Paper›PMID 39315107›Full record

ReviewFrontiers in immunology2024

Pharmacomicrobiomics in precision cancer therapy: bench to bedside.

Khanh Le Ngoc, Tran Thu Ha Pham, Tiep Khac Nguyen, Phung Thanh Huong

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Khanh Le Ngoc *Faculty of Biotechnology, Hanoi University of Pharmacy, Hanoi, Vietnam.
Tran Thu Ha Pham *Faculty of Biotechnology, Hanoi University of Pharmacy, Hanoi, Vietnam.
Tiep Khac NguyenFaculty of Biotechnology, Hanoi University of Pharmacy, Hanoi, Vietnam.
Phung Thanh HuongFaculty of Biotechnology, Hanoi University of Pharmacy, Hanoi, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The burgeoning field of pharmacomicrobiomics offers promising insights into the intricate interplay between the microbiome and cancer, shaping responses to diverse treatment modalities. This review aims to analyze the molecular mechanisms underlying interactions between distinct microbiota types and cancer, as well as their influence on treatment outcomes. We explore how the microbiome impacts antitumor immunity, and response to chemotherapy, immunotherapy, and radiation therapy, unveiling its multifaceted roles in cancer progression and therapy resistance. Moreover, we discuss the challenges hindering the development of microbiome-based interventions in cancer therapy, including standardization, validation, and clinical translation. By synthesizing clinical evidence, we underscore the transformative potential of harnessing pharmacomicrobiomics in guiding cancer treatment decisions, paving the way for improved patient outcomes in clinical practice.

Indexed as

NeoplasmsPrecision MedicineAnimalsAntineoplastic AgentsGastrointestinal MicrobiomeHumansImmunotherapyMicrobiotaTranslational Research, BiomedicalAntineoplastic Agentscancer therapymicrobiome interventionmicrobiotapharmacomicrobiomeprecision medicine

Identifiers

PMID39315107
PMCPMC11416994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.