Evidence map›Paper›PMID 39314980›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Dietary burden of phosphorus and aluminum in ready-to-eat wheat flour tortillas exceed that of corn tortillas: Implications for patients with renal or cardiovascular disease.

Kate C Chiang, Robert A Yokel, Jason M Unrine, Kamyar Kalantar-Zadeh, Ajay Gupta

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Kate C ChiangUniversity College Dublin School of Medicine, Dublin, Ireland.ORCID 0000-0003-0999-7516
Robert A YokelPharmaceutical Sciences, University of Kentucky, Lexington, Kentucky, 40536-0596.ORCID 0000-0001-5188-3972
Jason M UnrinePlant and Soil Sciences, University of Kentucky, Lexington, Kentucky, 40546-0091.ORCID 0000-0003-3012-5261
Kamyar Kalantar-ZadehDepartment of Epidemiology, University of California Los Angeles, California, USA, 90024.ORCID 0000-0002-8666-0725
Ajay GuptaDivision of Nephrology, Hypertension and Kidney Transplantation and Department of Medicine, University of California Irvine (UCI) School of Medicine, USA, 92697.ORCID 0000-0001-9182-3499

Funding

Pilot Project ProgramP30ES026529 · NIEHS · UNIVERSITY OF KENTUCKY · PI Jason Unrine · 2017 to 2026
$15.4M
NIEHS NIH HHS P30 ES026529
6 · The paper itself

Abstract

Ready-to-eat, shelf-stable tortillas contain several phosphorus- and aluminum-containing additives that may increase the risk of adverse events in patients with chronic kidney disease (CKD). The present study analyzes and compares the elemental content of wheat flour and corn tortillas with special reference to dietary aluminum and phosphorus burden. Twenty-one elements were quantified by ICP-MS and ICP-OES in 14 corn and 13 wheat flour tortilla brands purchased from local supermarkets in Southern California. The aluminum and phosphorus concentrations of many ready-to-eat tortilla brands can present a daily dietary load of up to approximately 100 mg aluminum and 700 mg phosphorus based on an average daily tortilla intake of 330 grams. Ready-to-eat wheat flour tortillas generally had more phosphorus than corn tortillas. Tortillas with aluminum listed as a food additive contained a higher aluminum content than those without such listing, exceeding the tolerable weekly intake. Despite conventional wisdom that CKD patients should avoid phosphorus-rich corn tortillas, ready-to-eat wheat flour tortillas consistently had a higher aluminum and phosphorus content due to additives. CKD patients and healthcare providers should pay attention to food labels, and regulatory authorities should monitor the use of approved food additives and mandate food label warnings for patients at risk.

Indexed as

aluminumchronic kidney diseasefood additivesphosphorustortilla

Identifiers

PMID39314980
PMCPMC11419229

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.