Evidence map›Paper›PMID 39314925›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2024

Malignancies After Lung Transplantation.

Caroline Stenman, Andreas Wallinder, Erik Holmberg, Kristjan Karason, Jesper Magnusson, Göran Dellgren

Abstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caroline StenmanTransplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden.
Andreas WallinderTransplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden.
Erik HolmbergRegional Cancer Center West, Region Västra Götaland, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Kristjan KarasonTransplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden.
Jesper MagnussonTransplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden.
Göran DellgrenTransplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung transplantation (LTx) is a well-known treatment for end-stage lung disease. This study aimed to report the incidence of cancer after LTx and long-term outcome among lung transplant recipients with a pretransplant diagnosis of cancer. Patients who underwent LTx between 1990-2016 were included in the study. Detection of cancer was obtained by cross-checking the study population with the Swedish Cancer Registry and the Cause-of-Death registry. A total of 614 patients were followed for a median of 5.1 years. In all, 159 malignancies were diagnosed. The excess risk of cancer or standardized incidence ratio (SIR) following LTx was 5.6-fold compared to the general Swedish population. The most common malignancies were non-melanoma skin cancer (NMSC) (SIR 76.5 (95%CI 61.7-94.8); non-Hodgkin lymphoma (SIR 23.5, 95%CI 14.8-37.2); and lung cancer (SIR 8.89, 95%CI 5.67-13.9). There was no significant difference in overall survival between those with and without a history of cancer before LTx (p = 0.56). In total, 159 malignancies were identified after LTx, which was a 5.6-fold higher relative to the general population. A history of previous cancer yields similar survival in selected recipients, compared to those without cancer prior to LTx.

Indexed as

Lung TransplantationRegistriesAdultAgedFemaleHumansIncidenceLung NeoplasmsMaleMiddle AgedNeoplasmsPostoperative ComplicationsRisk FactorsSkin NeoplasmsSwedenYoung Adultcancercohort studyepidemiologyheart transplantationimmunosuppression

Identifiers

PMID39314925
PMCPMC11417467

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.