Evidence map›Paper›PMID 39314625›Full record

ArticleFrontiers in physiology2024

Cognitive activity significantly affects the dynamic cerebral autoregulation, but not the dynamic vasoreactivity, in healthy adults.

Jasmin M Rizko, Lucy C Beishon, Ronney B Panerai, Vasilis Z Marmarelis

Abstract read
In one paragraph

Article in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jasmin M RizkoA. E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States.
Lucy C BeishonCerebral Haemodynamics in Ageing and Stroke Medicine Research Group, Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Ronney B PaneraiCerebral Haemodynamics in Ageing and Stroke Medicine Research Group, Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Vasilis Z MarmarelisA. E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States.

Funding

Mild Cognitive Impairment: Cerebrovascular Dysfunction and Exercise TrainingR01AG033106 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI LU, HANZHANG, ZHANG, RONG · 2009 to 2012
$3.1M
NIA NIH HHS R01 AG033106
6 · The paper itself

Abstract

Introduction: Neurovascular coupling (NVC) is an important mechanism for the regulation of cerebral perfusion during intensive cognitive activity. Thus, it should be examined in terms of its effects on the regulation dynamics of cerebral perfusion and its possible alterations during cognitive impairment. The dynamic dependence of continuous changes in cerebral blood velocity (CBv), which can be measured noninvasively using transcranial Doppler upon fluctuations in arterial blood pressure (ABP) and CO Methods: Using the Laguerre Expansion Technique (LET), this study extracted such models from data in supine resting vs cognitively active conditions (during attention, fluency, and memory tasks from the Addenbrooke's Cognitive Examination III, ACE-III) to elucidate possible changes in dCA and DVR due to cognitive stimulation of NVC. Healthy volunteers (n = 39) were recruited at the University of Leicester and continuous measurements of CBv, ABP, and EtCO Results: Modeling analysis of the dynamic ABP-to-CBv and CO Discussion: Interpretation of these changes through Principal Dynamic Mode (PDM) analysis is discussed in terms of possible associations between stronger NVC stimulation during cognitive tasks and enhanced sympathetic activation.

Indexed as

cerebral blood velocitydynamic cerebral autoregulationdynamic vasomotor reactivityneurovascular couplingtranscranial doppler ultrasonography

Identifiers

PMID39314625
PMCPMC11417032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.