Evidence map›Paper›PMID 39314446›Full record

ArticlebioRxiv : the preprint server for biology2024

Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection.

Ilya A Rybak, Natalia A Shevtsova, Johannie Audet, Sirine Yassine, Sergey N Markin, Boris I Prilutsky, Alain Frigon

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ilya A RybakDepartment of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, Pennsylvania 19129, USA.ORCID 0000-0003-3461-349X
Natalia A ShevtsovaDepartment of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, Pennsylvania 19129, USA.
Johannie AudetDepartment of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Centre de Recherche du CHUS, Université de Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada.ORCID 0000-0001-8519-3144
Sirine YassineDepartment of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Centre de Recherche du CHUS, Université de Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada.ORCID 0000-0003-1818-9553
Sergey N MarkinDepartment of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, Pennsylvania 19129, USA.
Boris I PrilutskySchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.ORCID 0000-0003-0499-3890
Alain FrigonDepartment of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Centre de Recherche du CHUS, Université de Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada.ORCID 0000-0002-9259-2706

Funding

Limb coordination during locomotion before and after spinal cord injuryR01NS110550 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI BORIS I PRILUTSKY, Ilya A Rybak · 2020 to 2026
$3.9M
NINDS NIH HHS R01 NS110550
6 · The paper itself

Abstract

Locomotion is controlled by spinal circuits that interact with supraspinal drives and sensory feedback from the limbs. These sensorimotor interactions are disrupted following spinal cord injury. The thoracic lateral hemisection represents an experimental model of an incomplete spinal cord injury, where connections between the brain and spinal cord are abolished on one side of the cord. To investigate the effects of such an injury on the operation of the spinal locomotor network, we used our computational model of cat locomotion recently published in

Indexed as

central pattern generatorcomputational modelhemisectionlocomotionsensorimotor interactionsspinal cord injurysplit-belt locomotion

Identifiers

PMID39314446
PMCPMC11419089

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.