Evidence map›Paper›PMID 39314354›Full record

ArticlebioRxiv : the preprint server for biology2024

ARHGEF3 Regulates Hair Follicle Morphogenesis.

Krithika Kalyanakrishnan, Amy Beaudin, Alexandra Jetté, Sarah Ghezelbash, Diana Ioana Hotea, Jie Chen, Philippe Lefrançois, Mélanie Laurin

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Krithika KalyanakrishnanCentre de recherche du CHU de Québec - Université Laval, axe Oncologie, Québec, Canada.
Amy BeaudinCentre de recherche du CHU de Québec - Université Laval, axe Oncologie, Québec, Canada.
Alexandra JettéCentre de recherche du CHU de Québec - Université Laval, axe Oncologie, Québec, Canada.ORCID 0000-0001-5423-2374
Sarah GhezelbashCancer Axis, Lady Davis Institute for Medical Research, Montreal, QC, Canada.
Diana Ioana HoteaCentre de recherche du CHU de Québec - Université Laval, axe Oncologie, Québec, Canada.
Jie ChenDepartment of Cell & Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0002-7887-3747
Philippe LefrançoisCancer Axis, Lady Davis Institute for Medical Research, Montreal, QC, Canada.ORCID 0000-0003-2939-7956
Mélanie LaurinCentre de recherche du CHU de Québec - Université Laval, axe Oncologie, Québec, Canada.ORCID 0000-0002-7198-3257

Funding

Phospholipase D signalingR01GM089771 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHEN, JIE · 2011 to 2025
$3.9M
NIGMS NIH HHS R01 GM089771
6 · The paper itself

Abstract

During embryogenesis, cells arrange into precise patterns that enable tissues and organs to develop specialized functions. Despite its critical importance, the molecular choreography behind these collective cellular behaviors remains elusive, posing a major challenge in developmental biology and limiting advances in regenerative medicine. By using the mouse hair follicle as a mini-organ system to study the formation of bud-like structures during embryonic development, our work uncovers a crucial role for the Rho GTPase regulator ARHGEF3 in hair follicle morphogenesis. We demonstrate that

Indexed as

ARHGEF3hair folliclemorphogenesisP-cadherinplacodeRhoGEFRho GTPase

Identifiers

PMID39314354
PMCPMC11419159

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.