ArticlebioRxiv : the preprint server for biology2024
The RNA helicase HrpA rescues collided ribosomes in
Annabelle Campbell, Hanna F Esser, A Maxwell Burroughs, Otto Berninghausen, L Aravind, Thomas Becker, Rachel Green, Roland Beckmann, Allen R Buskirk
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors.
Annabelle CampbellDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine; Baltimore, United States.
Hanna F EsserGene Center and Department of Biochemistry, University of Munich; Munich, Germany.
A Maxwell BurroughsComputational Biology Branch, Intramural Research Program, National Library of Medicine, National Institutes of Health; Bethesda, United States.
Otto BerninghausenGene Center and Department of Biochemistry, University of Munich; Munich, Germany.
L AravindComputational Biology Branch, Intramural Research Program, National Library of Medicine, National Institutes of Health; Bethesda, United States.
Thomas BeckerGene Center and Department of Biochemistry, University of Munich; Munich, Germany.
Rachel GreenDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine; Baltimore, United States.
Roland BeckmannGene Center and Department of Biochemistry, University of Munich; Munich, Germany.
Allen R BuskirkDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine; Baltimore, United States.
Funding
The role of collisions in rescuing stalled ribosomes in bacteriaR01GM136960 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Allen Rowdon Buskirk · 2021 to 2026
$1.9MThe role of HrpA in ribosome-associated quality control in E. coliF31AI172391 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CAMPBELL, ANNABELLE · 2022 to 2024
$124kNIAID NIH HHS F31 AI172391NIGMS NIH HHS R01 GM136960
6 · The paper itselfAbstract
Although many antibiotics inhibit bacterial ribosomes, loss of known factors that rescue stalled ribosomes does not lead to robust antibiotic sensitivity in
Identifiers
PMID39314269
PMCPMC11419001
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