Evidence map›Paper›PMID 39314243›Full record

ArticleiScience2024

CXCR4-enriched T regulatory cells preferentially home to bone marrow and resolve inflammation.

Meixian Huang, Zeng Ke, Mi-Ae Lyu, Lucia Masarova, Tara Sadeghi, Christopher R Flowers, Simrit Parmar

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Immunotherapy in central nervous system tumors.International journal of surgery (London, England) · 2025
    Review
  7. Article
  8. Blocking CXCR4Genome medicine · 2025
    Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meixian HuangDepartment of Lymphoma/ Myeloma, MD Anderson Cancer Center, Houston, TX, USA.
Zeng KeDepartment of Lymphoma/ Myeloma, MD Anderson Cancer Center, Houston, TX, USA.
Mi-Ae LyuDepartment of Lymphoma/ Myeloma, MD Anderson Cancer Center, Houston, TX, USA.
Lucia MasarovaDepartment of Leukemia, MD Anderson Cancer Center, Houston, TX, USA.
Tara SadeghiCellenkos Inc., Houston, TX, USA.
Christopher R FlowersDepartment of Lymphoma/ Myeloma, MD Anderson Cancer Center, Houston, TX, USA.
Simrit ParmarDepartment of Lymphoma/ Myeloma, MD Anderson Cancer Center, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CXCR4 cell surface expression is critical for the homing of T regulatory (Treg) cells to the bone marrow (BM). We hypothesize that CXCR4 enrichment on Tregs cell surface may abbreviate their transit time to reach BM. Umbilical cord-blood CD25

Indexed as

Cell biologyImmunityImmunology

Identifiers

PMID39314243
PMCPMC11418154

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.