Evidence map›Paper›PMID 39314082›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2024

Substantiating the Short Burst Duration in Cortical Myoclonus.

Sterre van der Veen, Amber Maliepaard, Madelein van der Stouwe, Jelle Dalenberg, Inge Tuitert, Jan Willem J Elting, Marina A J Tijssen

Abstract read
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Recent advances in clinical neurophysiology of myoclonus.Clinical parkinsonism & related disorders · 2026
    Article
  3. Benign Idiopathic Myoclonus: A New Clinical Entity?Movement disorders clinical practice · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sterre van der VeenDepartment of Neurology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.ORCID 0000-0003-0698-2087
Amber MaliepaardDepartment of Neurology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.
Madelein van der StouweDepartment of Neurology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.ORCID 0000-0001-9497-2019
Jelle DalenbergDepartment of Neurology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.
Inge TuitertDepartment of Neurology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.
Jan Willem J EltingDepartment of Neurology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.
Marina A J TijssenDepartment of Neurology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.ORCID 0000-0001-5783-571X

Funding

samenwerkingsverband noord-nederland (SNN) 01492947ZonMw 91218013
6 · The paper itself

Abstract

backgroundMyoclonus is characterized by involuntary, shock-like movements, of which cortical (CM) and non-cortical myoclonus (NCM) are most common. Electrophysiology can help differentiate between these subtypes; however, the diagnostic value of several features is largely unknown.

objectiveThis study aims to determine the diagnostic value of the burst duration in distinguishing CM and NCM.

methodsWe manually identified the burst duration of 8 patients with CM, confirmed by electromyography-electroencephalography registration or somatosensory-evoked potentials, and 19 patients with NCM, suspected due to a myoclonus-dystonia phenotype (MYC/DYT-SGCE positive and negative).

resultsThe sensitivity and specificity were calculated to assess the diagnostic value. The burst duration of CM (31.1 ms) was significantly shorter than that of NCM (56.7 ms), with a sensitivity of 100% and a specificity of 89.5% at a threshold of 45.0 ms. A minimum of 10 randomly selected bursts were sufficient for reliable diagnostic accuracy.

conclusionThe burst duration seems a valuable supportive diagnostic criterion for distinguishing CM and NCM.

Indexed as

ElectroencephalographyElectromyographyEvoked Potentials, SomatosensoryMyoclonusAdolescentAdultAgedCerebral CortexFemaleHumansMaleMiddle AgedSensitivity and SpecificityYoung Adultanatomical classificationburst durationcortical myoclonuselectromyographymyoclonus

Identifiers

PMID39314082
PMCPMC11657038

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.