Evidence map›Paper›PMID 39313893›Full record

ReviewCentral nervous system agents in medicinal chemistry2025

The Effect of Probiotics and Microbiota on Nervous System and Mental Illnesses.

Hadi Hossainpour, Salman Khazaei, Hassan Mahmoudi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Central nervous system agents in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hadi HossainpourDepartment of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Salman KhazaeiDepartment of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
Hassan MahmoudiDepartment of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Funding

Vice Chancellor for Research & Technology of Hamadan University of Medical Sciences, Hamadan, Iran IR.UMSHA.REC.1401.640
6 · The paper itself

Abstract

The microbiota that inhabits the gastrointestinal tract has been linked to various gastrointestinal and non-gastrointestinal disorders. Scientists have been studying how the bacteria in our intestines have an effect on our brain and nervous system. This connection is called the "microbiota-gut-brain axis". Given the capacity of probiotics, which are live non-pathogenic microorganisms, to reinstate the normal microbial population within the host and confer advantages, their potential impact has been subjected to scrutiny with regard to neurological and mental conditions. Material sourced for this review included peer-reviewed literature annotated in the PubMed, Web of Science, Scopus, and Google Scholar databases. The result has indicated the integration of probiotics into a child's diet to enhance the neuro-behavioral symptoms. Notwithstanding this, the current data set has been found to be insufficient and inconclusive. The potential utility of probiotics for the prevention or treatment of neurologic and mental disorders has become a subject of substantial interest.

Indexed as

Gastrointestinal MicrobiomeMental DisordersNervous System DiseasesProbioticsAnimalsHumansmental illnessesmicrobiotamicrobiota-gut-brain axisneurological disordersnon-pathogenic microorganisms.Probiotics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.