Evidence map›Paper›PMID 39313889›Full record

ArticleInfectious disorders drug targets2025

Investigating the Efficacy of Various Natural Products in Raw Form against Multidrug-Resistant Bacteria.

Hamad H Alanazi, Hussain Ali G Aldughmani, Bi Bi Zianab Mazhari

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infectious disorders drug targets, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hamad H AlanaziDepartment of Clinical Laboratory Science, College of Applied Medical Sciences-Qurayyat, Jouf University, Al Jouf, Saudi Arabia.
Hussain Ali G AldughmaniDepartment of Microbiology, Quryyat Hospital, Quryyat Regional Laboratory, Al Qurayyat, Saudi Arabia.
Bi Bi Zianab MazhariDepartment of Clinical Laboratory Science, College of Applied Medical Sciences-Qurayyat, Jouf University, Al Jouf, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe alarming increase in antibiotic resistance urges alternative and efficacious antimicrobial solutions. Historically, medicinal plants have been used for therapeutic purposes, such as relieving pain and healing wounds. The evaluation of the natural therapeutic effects of medicinal plants in a manner that resembles how humans typically consume them is lacking. In this study, many medicinal plants known to have some antimicrobial effects, including Frankincense, Garlic, Myrrh, and Ginger, were evaluated for their direct antibacterial activity in raw form. MATERIALS AND

methodsThe direct antimicrobial activity of medicinal plants was evaluated against a variety of Gram-positive and Gram-negative bacterial strains, such as

resultsOut of all the tested medicinal plants, only raw garlic

conclusionOnly garlic in its raw form was effective against antibiotic-resistant bacteria. The increase in the antibacterial activity of garlic when combined with vinegar suggests synergistic activity of garlic. The straightforward antibacterial action of raw garlic may be strategically harnessed to combat the continuous challenge of increasing antibiotic resistance. This work promotes additional testing of more natural products (in raw form) and assesses their therapeutic effects clinically.

Indexed as

Anti-Bacterial AgentsBiological ProductsDrug Resistance, Multiple, BacterialGram-Negative BacteriaGram-Positive BacteriaPlant ExtractsPlants, MedicinalAcetic AcidAcinetobacter baumanniiGarlicHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsStaphylococcus aureusAcetic AcidAnti-Bacterial AgentsBiological ProductsPlant Extractsallium sativumantibiotic resistanceantibiotics.antimicrobial drugsgarlicnatural productsPhytochemicals

Identifiers

PMID39313889
PMCPMC11851147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.