Evidence map›Paper›PMID 39313803›Full record

Observational studyBMC complementary medicine and therapies2024

Use of complementary and alternative medicine in patients with chronic liver diseases in Germany- a multicentric observational study.

Fleur Sophie Gittinger, Anna Rahnfeld, Elena Lacruz, Alexander Zipprich, Frank Lammert, Cristina Ripoll

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC complementary medicine and therapies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fleur Sophie Gittinger *Martin-Luther-University Clinic Halle (-Saale), Innere Medizin I (Gastroenterology, Hepatology, Pneumology), Halle, Germany. fleursophie.gittinger@sanktgeorg.de.
Anna Rahnfeld *Martin-Luther-University Clinic Halle (-Saale), Innere Medizin I (Gastroenterology, Hepatology, Pneumology), Halle, Germany.
Elena LacruzMartin-Luther-University Clinic Halle (-Saale), Medical Epidemiology, Biometrics and Computer Sciences, Halle, Germany.
Alexander ZipprichMartin-Luther-University Clinic Halle (-Saale), Innere Medizin I (Gastroenterology, Hepatology, Pneumology), Halle, Germany.
Frank LammertUniversity Clinic of the Saarland, Innere Medizin II (Gastroenterology, Hepatology, Endocrinology, Diabetology and Nutritional Sciences), Homburg, Germany.
Cristina RipollMartin-Luther-University Clinic Halle (-Saale), Innere Medizin I (Gastroenterology, Hepatology, Pneumology), Halle, Germany. cristina.ripoll@med.uni-jena.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of Complementary and alternative medicine (CAM) in chronic liver disease (CLD) patients in Germany is unknown. This study investigated the frequency of CAM use and associated sociodemographic, clinical and personality factors in CLD patients in Germany.

methodsThis is a cross-sectional multicenter study of CLD patients attending liver outpatient clinics of university hospitals in Halle(-Saale) and Homburg between 2015 and 2017. Dedicated questionnaires recorded CAM use, sociodemographic and personality factors (evaluated with the "Big five" model, "Hospital Anxiety and Depression"-, "Multidimensional Health Locus of Control"- score). Uni- and multivariate analyses assessed factors associated to CAM use.

resultsOverall 378 patients were recruited, 92 (24.3%) reported to CAM use. On univariate analysis, female CAM users were older (p = 0.001) and more physically active (p = 0.002), male CAM users more often used homeopathy (p = 0.000), actively promoted their health (p = 0.010) or had UDC in their medication (p = 0.004). Logistic regression analysis adjusted for personality factors showed significant association of age, physical exercise (females) and satisfaction with alternative medicine (females, males) to CAM use.

conclusionsCAM use is prevalent among CLD patients in Germany and is significantly associated to satisfaction with alternative medicine (females, males), physical exercise and older age (females). Doctors should actively inquire CLD patients about CAM use, as hepatotoxicity or interaction with medication can occur.

Indexed as

Complementary TherapiesLiver DiseasesAdultAgedChronic DiseaseCross-Sectional StudiesFemaleGermanyHumansMaleMiddle AgedPatient SatisfactionSurveys and QuestionnairesCAMChronic liver disease

Identifiers

PMID39313803
PMCPMC11421120

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.