Evidence map›Paper›PMID 39313714›Full record

ArticleJournal of assisted reproduction and genetics2024

Comparison of the developmental competence of in vitro-produced mouse embryos cultured under 5 versus 2% O

Jacob Varghese, Brad Link, Ben Wong, Jacob C Thundathil

Abstract readComparative Study
In one paragraph

Article in Journal of assisted reproduction and genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jacob VargheseFaculty of Veterinary Medicine, University of Calgary, Calgary, AB, T2N 4N1, Canada.ORCID http://orcid.org/0009-0001-2750-3981
Brad LinkRegional Fertility Program, 2000 Veterans Pl NW #400, Calgary, AB, T3B 4N2, Canada.
Ben WongRegional Fertility Program, 2000 Veterans Pl NW #400, Calgary, AB, T3B 4N2, Canada.
Jacob C ThundathilFaculty of Veterinary Medicine, University of Calgary, Calgary, AB, T2N 4N1, Canada. jthundat@ucalgary.ca.

Funding

Agriculture and Agri-Food Canada Grant #: YESP2021-1564-NW
6 · The paper itself

Abstract

purposeThe prevalence of infertility in Canada has substantially increased over 30 years, and plateaued success rates of culture systems warrant further optimization for transfer outcomes. In clinical programs, embryos commonly undergo extended culture under 5% O

methodsQuantitative measures of development and relative expressions of a cohort of stress-related genes in CD1 mouse zygotes cultured to blastocysts under 5 or 2% O

resultsThe mean percentage of blastocysts developed, and total cell number of embryos derived in vivo or cultured under 5% O

conclusionWe inferred that 5% O

Indexed as

ApoptosisBlastocystEmbryo Culture TechniquesEmbryonic DevelopmentFertilization in VitroOxygenAnimalsEmbryo TransferFemaleGene Expression Regulation, DevelopmentalHumansMicePregnancyOxygenBlastocystIn vitro cultureMouseOxygen

Identifiers

PMID39313714
PMCPMC11621300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.