Evidence map›Paper›PMID 39313704›Full record

ArticleProbiotics and antimicrobial proteins2025

Administration of Lacticaseibacillus casei CSL3 in Swiss Mice with Immunosuppression Induced by Cyclophosphamide: Effects on Immunological, Biochemical, Oxidative Stress, and Histological Parameters.

Khadija Bezerra Massaut, Helena Reissing Soares Vitola, Vitória Sequeira Gonçalves, Fabio Pereira Leivas Leite, Rodrigo Desessards Jardim, Ângela Nunes Moreira, Wladimir Padilha da Silva, Ângela Maria Fiorentini

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khadija Bezerra MassautLaboratory of Food Microbiology, Department of Agroindustrial Science and Technology, Federal University of Pelotas, Pelotas, RS, Brazil.ORCID http://orcid.org/0000-0003-0531-4220
Helena Reissing Soares VitolaLaboratory of Food Microbiology, Department of Agroindustrial Science and Technology, Federal University of Pelotas, Pelotas, RS, Brazil.ORCID http://orcid.org/0000-0002-6631-7372
Vitória Sequeira GonçalvesBiotechnology Unit, Technology Development Center, Federal University of Pelotas, Pelotas, RS, Brazil.ORCID http://orcid.org/0000-0003-1639-2494
Fabio Pereira Leivas LeiteBiotechnology Unit, Technology Development Center, Federal University of Pelotas, Pelotas, RS, Brazil.ORCID http://orcid.org/0000-0003-0941-7286
Rodrigo Desessards JardimHistology Laboratory, Institute of Biological Sciences, Federal University of Rio Grande, Rio Grande, RS, Brazil.ORCID http://orcid.org/0000-0003-2448-6749
Ângela Nunes MoreiraLaboratory of Applied Immunology, Biotechnology Unit, Technology Development Center, Federal University of Pelotas, Pelotas, RS, Brazil.ORCID http://orcid.org/0000-0001-5347-8559
Wladimir Padilha da SilvaLaboratory of Food Microbiology, Department of Agroindustrial Science and Technology, Federal University of Pelotas, Pelotas, RS, Brazil.ORCID http://orcid.org/0000-0002-4276-2690
Ângela Maria FiorentiniLaboratory of Food Microbiology, Department of Agroindustrial Science and Technology, Federal University of Pelotas, Pelotas, RS, Brazil. angefiore@gmail.com.ORCID http://orcid.org/0000-0003-3945-0079

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

The study aimed to evaluate the effects of supplementation with Lacticaseibacillus casei CSL3 in Swiss mice immunosuppressed with cyclophosphamide on immunological, biochemical, oxidative stress, and histological parameters. The animals were distributed into four groups (control, CSL3, cyclophosphamide, and CSL3 + cyclophosphamide), where two groups were treated with L. casei CSL3 (10 log CFU mL

Indexed as

CyclophosphamideImmunityLacticaseibacillus caseiProbioticsAnimalsAntineoplastic Agents, AlkylatingBlood Cell CountFecesIntestinesKidneyLipid MetabolismLiverMaleMiceOxidative StressSpleenAntineoplastic Agents, AlkylatingCyclophosphamideThiobarbituric Acid Reactive SubstancesChemotherapyFecesInterleukinsIn vivo modelProbioticsSerum analysis

Identifiers

PMID39313704

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.