Evidence map›Paper›PMID 39313604›Full record

ArticleInnere Medizin (Heidelberg, Germany)2025

[Hepatotoxicity due to albendazole: safe alternatives for echinococcosis therapy].

Laura Muana Wilhelm, Joschka Bachmann, Markus Cornberg, Heiner Wedemeyer, Bernd Heinrich

Abstract readCase ReportsEnglish Abstract
In one paragraph

Article in Innere Medizin (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laura Muana WilhelmKlinik für Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie, Medizinische Hochschule Hannover (MHH), OE 6810, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Joschka BachmannKlinik für Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie, Medizinische Hochschule Hannover (MHH), OE 6810, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Markus CornbergKlinik für Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie, Medizinische Hochschule Hannover (MHH), OE 6810, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Heiner WedemeyerKlinik für Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie, Medizinische Hochschule Hannover (MHH), OE 6810, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Bernd HeinrichKlinik für Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie, Medizinische Hochschule Hannover (MHH), OE 6810, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. heinrich.bernd@mh-hannover.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection with Echinococcus multilocularis leads to the clinical manifestation of alveolar echinococcosis. This is characterized by the formation of alveolar liver tumours, which usually disintegrate necrotically in the course of the disease. Pseudocysts are formed. Especially in the early stages, curative resection followed by long-term treatment with albendazole is recommended. However, the majority of patients are not amenable to curative surgery. In these cases, albendazole therapy is the first-choice treatment. We present a rare case of albendazole-associated hepatitis in a patient with inoperable Echinococcus multilocularis infection, with a favourable outcome following a change in treatment to mebendazole.

Indexed as

AlbendazoleAnthelminticsChemical and Drug Induced Liver InjuryEchinococcosisEchinococcosis, HepaticAnimalsEchinococcus multilocularisHumansMebendazoleAlbendazoleAnthelminticsMebendazoleAlbendazole-associated hepatitisAlbendazole-associated toxicityAlveolar echinococcosisEchinococcus multilocularisMebendazole

Identifiers

PMID39313604
PMCPMC11799110

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.