Evidence map›Paper›PMID 39313442›Full record

ReviewCancer control : journal of the Moffitt Cancer Center

Cancer Therapeutic Potential and Prognostic Value of the SLC25 Mitochondrial Carrier Family: A Review.

Renzhuo Gao, Dan Zhou, Xingpeng Qiu, Jiayi Zhang, Daya Luo, Xiaohong Yang, Caiyun Qian, Zhuoqi Liu

Abstract readReview
In one paragraph

Review in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Renzhuo GaoSchool of Queen Mary, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID 0009-0007-3936-0096
Dan ZhouSchool of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID 0009-0007-4415-5409
Xingpeng QiuSchool of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID 0009-0006-3698-2036
Jiayi ZhangSchool of Queen Mary, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID 0009-0004-8210-5646
Daya LuoSchool of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID 0000-0003-1227-2436
Xiaohong YangSchool of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID 0000-0001-6985-3173
Caiyun QianDepartment of Blood Transfusion, Key Laboratory of Jiangxi Province for Transfusion Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Zhuoqi LiuSchool of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID 0000-0002-7293-0886

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transporters of the solute carrier family 25 (SLC25) regulate the intracellular distribution and concentration of nucleotides, amino acids, dicarboxylates, and vitamins within the mitochondrial and cytoplasmic matrices. This mechanism involves changes in mitochondrial function, regulation of cellular metabolism, and the ability to provide energy. In this review, important members of the SLC25 family and their pathways affecting tumorigenesis and progression are elucidated, highlighting the diversity and complexity of these pathways. Furthermore, the significant potential of the members of SLC25 as both cancer therapeutic targets and biomarkers will be emphasized.

Indexed as

NeoplasmsBiomarkers, TumorHumansMitochondriaMitochondrial Membrane Transport ProteinsMitochondrial ProteinsOrganic Anion TransportersPrognosisBiomarkers, TumorMitochondrial Membrane Transport ProteinsMitochondrial ProteinsOrganic Anion TransportersSlc25a1 protein, humanbiomarkersmitochondrial carrier familymitochondrial functionsolute carrier family 25therapeutic targets

Identifiers

PMID39313442
PMCPMC11439189

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.