Evidence map›Paper›PMID 39313283›Full record

Observational studyBMJ open2024

Cohort profile: the Swiss Mother and Child HIV Cohort Study (MoCHiV).

Paolo Paioni, Murezi Capaul, Anja Brunner, Anna Traytel, Karoline Aebi-Popp, Pierre-Alex Crisinel, Andrea Duppenthaler, Huldrych Günthard, Begona Martinez De Tejada, Lisa Kottanattu and 9 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Breastfeeding in Women Living With HIV in the ART Era: Toward Risk-Adapted Clinical Care.Journal of the International Association of Providers of AIDS Care
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Paolo PaioniDivision of Infectious Diseases and Hospital Epidemiology, University Children's Hospital Zurich, Zurich, Switzerland.
Murezi CapaulDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Anja BrunnerFrauenklinik, Bürgerspital Solothurn, Solothurn, Switzerland.
Anna TraytelDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Karoline Aebi-PoppDepartment of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland.
Pierre-Alex CrisinelUnit of Pediatric Infectious Diseases and Vaccinology, Department of Woman Mother and Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Andrea DuppenthalerDepartment of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Huldrych GünthardDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Begona Martinez De TejadaObstetrics Division. Department of Pediatrics, Gynecology and Obstetrics, University Hospitals Geneva, University of Geneva, Geneva, Switzerland.
Lisa KottanattuInstitute of Pediatrics of Southern Switzerland, EOC, Bellinzona, Switzerland.
Marcel StöckleDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University Basel, Basel, Switzerland.
Andri RauchDepartment of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland.
Noemie WagnerPediatric Infectious Diseases Unit, Department of Pediatrics, Gynecology and Obstetrics, Geneva University Hospitals, Geneve, Switzerland.
Irene HösliDepartment of Obstetrics, University Hospital Basel, Basel, Switzerland.
Christoph RudinUniversity Children's Hospital Basel, Basel, Switzerland.
Alexandra ScherrerDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Katharina KusejkoDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Christian R KahlertCantonal Hospital St. Gallen, Department of Infectious Diseases, Infection Prevention and Travel Medicine, St Gallen, Switzerland christian.kahlert@kispisg.ch.ORCID 0000-0002-0784-3276
Swiss HIV Cohort Study (SHCS) and the Swiss Mother and Child HIV Cohort Study (MoCHiV)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeProspective, multicentric observational cohort study in Switzerland investigating measures to prevent mother-to-child transmission in pregnant women with HIV (WWH) and assessing health and development of their exposed children as well as of children with HIV (CWH) in general.

participantsBetween January 1986 and December 2022, a total of 1446 mother-child pairs were enrolled. During the same period, the study also registered 187 CWH and 521 HIV-exposed but uninfected children (HEU), for whom detailed maternal information was not available. Consequently, the cohort comprises a total of 2154 children. FINDINGS TO DATE: During these 37 years, research by the Swiss Mother and Child HIV Cohort Study (MoCHiV) and its international collaborators has strongly influenced the prevention of vertical transmission of HIV (eg, introduction and discontinuation of elective caesarean section, neonatal postexposure prophylaxis and breastfeeding). Contributions have also been made to the management of diagnostics (eg, p24 antigen assay) and the effects of antiretroviral treatment (eg, prematurity, growth) in HEU and CWH. FUTURE PLANS: Most children present within the cohort are now HEU, highlighting the need to investigate other vertically transmitted pathogens such as hepatitis B and C viruses, cytomegalovirus or

Indexed as

HIV InfectionsInfectious Disease Transmission, VerticalPregnancy Complications, InfectiousAdultBreast FeedingChildChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornMalePregnancyProspective StudiesSwitzerlandChildHIV & AIDSPregnant Women

Identifiers

PMID39313283
PMCPMC11418562

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.