Evidence map›Paper›PMID 39312769›Full record

ArticleJMIR dermatology2024

Effectiveness of 675-nm Wavelength Laser Therapy in the Treatment of Androgenetic Alopecia Among Indian Patients: Clinical Experimental Study.

B S Chandrashekar, Oliver Clement Lobo, Irene Fusco, Francesca Madeddu, Tiziano Zingoni

Abstract read
In one paragraph

Article in JMIR dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. High-powered 675-nm laser: Safety and efficacy in clinical evaluation and in vitro evidence for different skin disorders.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

B S ChandrashekarCutis Academy of Cutaneous Sciences, Bengaluru, India.ORCID 0000-0001-9593-8875
Oliver Clement LoboCutis Academy of Cutaneous Sciences, Bengaluru, India.ORCID 0009-0005-2578-4256
Irene FuscoEl.En. Group, Calenzano, Italy.ORCID 0000-0001-7264-8808
Francesca MadedduEl.En. Group, Calenzano, Italy.ORCID 0009-0009-5386-7656
Tiziano ZingoniEl.En. Group, Calenzano, Italy.ORCID 0009-0008-8688-7787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAndrogenetic alopecia (AGA) is the most prevalent cause of hair loss around the world.

objectiveThe purpose of this study was to evaluate the efficacy of laser stimulation with a 675-nm wavelength for the treatment of AGA in male and female Indian patients.

methodsA total of 20 Indian healthy patients aged 23-57 years who presented a grade of alopecia stage I to stage V underwent one single pass with a 675-nm laser to the scalp area twice a week for a total of 8 sessions, followed by once a week for 4 sessions and once in 2 weeks for 2 sessions. There are 14 laser treatments in total. Macro- and dermatoscopic images have been acquired at T0 (baseline) and T1 (4 months). The vertex, frontal, and parietal areas of the scalp were evaluated. Many parameters were analyzed including hair count and hair density of terminal; mean thickness; vellus follicles; total follicular units; units with 1 hair, 2 hairs, 3 hairs, 4 hairs, and >4 hairs; unit density; and average hair/unit.

resultsThe macroimages and dermatoscopic evaluations showed good improvement over the entire treated area, with a clear increase in the number of hairs and hair thickness. General parameters such as hair count and hair density showed a percentage increase of around 17%. The hair mean thickness parameters showed a significant (P<.001) percentage increase of 13.91%. Similar results were obtained for terminal and vellus hair: terminal hair count and hair density significantly (P=.04 and P=.01, respectively) increased by 17.45%, vellus hair count increased by 16.67% (P=.06), and the density of vellus hair increased by 16.61% (P=.06).

conclusionsThe study findings demonstrate that the 675-nm laser system improved AGA in Indian patients, facilitating the anagen phase and improving hair density and other positive hair parameters.

Indexed as

AlopeciaAdultDermoscopyFemaleHairHumansIndiaLow-Level Light TherapyMaleMiddle AgedScalpTreatment OutcomeYoung Adult675-nm laserAGAandrogenetic alopeciaeffectivenesshairhair densityhair losshair restorationIndiaIndianIndian patientslaser stimulationlaser therapypatientpatientstherapytreatment

Identifiers

PMID39312769
PMCPMC11459112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.