Evidence map›Paper›PMID 39312184›Full record

ArticleBiomacromolecules2024

Effects of Secondary Amine and Molecular Weight on the Biological Activities of Cationic Amphipathic Antimicrobial Macromolecules.

Zeyu Shao, Hao Luo, Thi Hanh Quyen Nguyen, Edgar H H Wong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Antimicrobial Cyclic Peptidomimetics.Macromolecular rapid communications · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zeyu ShaoSchool of Chemical Engineering, University of New South Wales (UNSW), Sydney, NSW 2052, Australia.
Hao LuoSchool of Chemical Engineering, University of New South Wales (UNSW), Sydney, NSW 2052, Australia.
Thi Hanh Quyen NguyenSchool of Chemical Engineering, University of New South Wales (UNSW), Sydney, NSW 2052, Australia.
Edgar H H WongSchool of Chemical Engineering, University of New South Wales (UNSW), Sydney, NSW 2052, Australia.ORCID 0000-0001-5151-5045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cationic amphipathic antimicrobial agents inspired by antimicrobial peptides (AMPs) have shown potential in combating multidrug-resistant bacteria because of minimal resistance development. Here, this study focuses on the development of novel cationic amphipathic macromolecules in the form of dendrons and polymers with different molecular weights that employ secondary amine piperidine derivative as the cationic moiety. Generally, secondary amine compounds, especially at low molecular weights, have stronger bacteriostatic, bactericidal, and inner membrane disruption abilities than those of their primary amine counterparts. Low molecular weight

Indexed as

AminesEscherichia coliMicrobial Sensitivity TestsMolecular WeightAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial Cationic PeptidesCationsDendrimersHumansHydrophobic and Hydrophilic InteractionsRifampinAminesAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial Cationic PeptidesCationsDendrimersRifampin

Identifiers

PMID39312184
PMCPMC11483101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.