Evidence map›Paper›PMID 39311917›Full record

ReviewDer Nervenarzt2025

[Life style drug laughing gas (nitrous oxide, N

Dominik Diesing, Peter Neu

Abstract readEnglish AbstractReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Der Nervenarzt, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. [Lethal nitrous oxide].Der Nervenarzt · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dominik DiesingKlinik für Psychiatrie und Psychotherapie, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Deutschland. dominik.diesing@charite.de.
Peter NeuKlinik für Psychiatrie und Psychotherapie, Jüdisches Krankenhaus Berlin, Berlin, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe increasing popularity of nitrous oxide (N MATERIAL AND

methodsA comprehensive literature search until April 2024 was conducted to identify publications addressing N

resultsStudies showed mixed results regarding craving and loss of control among N DISCUSSION: The data on the dependency potential of N

conclusionNitrous oxide is currently primarily regarded as a substance of abuse with the potential to foster psychological dependence, manifesting particularly through loss of control and neglect; however, the criteria for physical dependence, such as the occurrence of withdrawal syndromes and the development of tolerance, have not yet been convincingly documented. Further research is needed to better understand the dependency potential of N

Indexed as

Illicit DrugsInternational Classification of DiseasesNitrous OxideSubstance-Related DisordersHumansSubstance Withdrawal SyndromeIllicit DrugsNitrous OxideAdolescent behavior, drug effectsNeurological manifestations, drug effectsNitrous oxide, adverse effectsSubstance abuse, psychologySubstance-related disorders, psychology

Identifiers

PMID39311917
PMCPMC12058959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.