Evidence map›Paper›PMID 39311789›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2024

Two-sample Mendelian randomization analysis of causal relationship between eczema and autoimmune diseases.

Chunli Chen, Siyu Yan, Bangbei Wan, Yangyiyi Yu, Jinrong Zeng, Lina Tan, Jianyun Lu

Abstract read
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chunli ChenDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013. 1985540159@qq.com.
Siyu YanDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013. sunshine0719happy@163.com.
Bangbei WanReproductive Medical Center, Hainan Women and Children's Medical Center, Haikou 570208, China.
Yangyiyi YuDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013.
Jinrong ZengDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013.
Lina TanDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013. tanlinawork@163.com.
Jianyun LuDepartment of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013. xiaoyun3@csu.edu.cn.

Funding

the Hunan Provincial Health Commission Scientific Research Plan Project D202304128334the National Natural Science Foundation 82273506 and 82273508
6 · The paper itself

Abstract

objectivesThe causal relationship between eczema and autoimmune diseases has not been previously reported. This study aims to evaluate the causal relationship between eczema and autoimmune diseases.

methodsThe two-sample Mendelian randomization (MR) method was used to assess the causal effect of eczema on autoimmune diseases. Summary data from the Genome-Wide Association Study Catalog (GWAS) were obtained from the Integrative Epidemiology Unit (IEU) database. For eczema and autoimmune diseases, genetic instrument variants (GIVs) were identified according to the significant difference (

resultsGenetic susceptibility to eczema was associated with an increased risk of Crohn's disease (

conclusionsEczema is associated with an increased risk of Crohn's disease and ulcerative colitis. No causal relationship is found between eczema and SLE, MS, AS, RA, BP, or vitiligo.

Indexed as

Autoimmune DiseasesCrohn DiseaseEczemaGenetic Predisposition to DiseaseGenome-Wide Association StudyMendelian Randomization AnalysisArthritis, RheumatoidColitis, UlcerativeHumansLupus Erythematosus, SystemicMultiple SclerosisPemphigoid, BullousPolymorphism, Single NucleotideRisk FactorsSpondylitis, Ankylosingatopic eczemaautoimmune diseasesCrohn’s diseaseeczemaMendelian randomizationulcerative colitis

Identifiers

PMID39311789
PMCPMC11420964

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.