Evidence map›Paper›PMID 39311468›Full record

ArticleAmerican journal of men's health

Screening of the Combined Risk of Genetics and Epidemiology on Infertility Among Indian Men: Synergistic Effect of AZFc Partial Deletions and Habits of Smokeless Chewing Tobacco.

Saurav Dutta, Pranab Paladhi, Samudra Pal, Souvik Srimani, Gunja Bose, Papiya Ghosh, Ratna Chattopadhyay, Sujay Ghosh

Abstract read
In one paragraph

Article in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Saurav DuttaCytogenetics and Genomics Research Unit, Department of Zoology, University of Calcutta, Kolkata, India.
Pranab PaladhiCytogenetics and Genomics Research Unit, Department of Zoology, University of Calcutta, Kolkata, India.
Samudra PalCytogenetics and Genomics Research Unit, Department of Zoology, University of Calcutta, Kolkata, India.
Souvik SrimaniCytogenetics and Genomics Research Unit, Department of Zoology, University of Calcutta, Kolkata, India.
Gunja BoseInstitute of Reproductive Medicine (IRM), Salt Lake City, Kolkata, India.
Papiya GhoshDepartment of Zoology, Bijoy Krishna Girls' College (Affiliated to University of Calcutta), Howrah, India.
Ratna ChattopadhyayInstitute of Reproductive Medicine (IRM), Salt Lake City, Kolkata, India.
Sujay GhoshCytogenetics and Genomics Research Unit, Department of Zoology, University of Calcutta, Kolkata, India.ORCID 0000-0003-1703-8446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The AZFc partial deletions of Y chromosome and lifestyle/epidemiological factors such as the use of smokeless chewing tobacco (SCT) exhibit intriguing variations in their association with male infertility across the population, ethnicity, and genetic background. Here, a pioneering attempt has been made to elucidate the interactions of such deletions with the habits of SCT consumption among the participating individuals, using their large epidemiological data. This screening program was conducted among Bengali-speaking men in West Bengal, India. We screened the prevalence and association of distinct partial deletions (gr/gr, b1/b3, and b2/b3) of the AZFc region using locus-specific sequence-tagged site (STS) markers among 728 case subjects and compared them with 264 ethnicity- and age-matched proven-fertile control men. The recorded epidemiological data of the study group and the outcome of partial deletion analysis were compiled to frame the plausible Gene × Epidemiological factor (G × E) interactions. The gr/gr deletion was reported to be significantly associated with azoospermic (

Indexed as

Chromosomes, Human, YInfertility, MaleTobacco, SmokelessAdultCase-Control StudiesChromosome DeletionHumansIndiaMaleSex Chromosome AberrationsSex Chromosome Disorders of Sex DevelopmentAZFc partial deletionazoospermiagene–environment interactionmale infertilitysmokeless tobacco

Identifiers

PMID39311468
PMCPMC11437552

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.