Evidence map›Paper›PMID 39311362›Full record

ArticleInternational journal of neonatal screening2024

Consistency in the Assessment of Dried Blood Spot Specimen Size and Quality in U.K. Newborn Screening Laboratories.

Stuart J Moat, James R Bonham, Christine Cavanagh, Margaret Birch, Caroline Griffith, Lynette Shakespeare, Clare Le Masurier, Claire Manfredonia, Beverly Hird, Philippa Goddard and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of neonatal screening, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Stuart J MoatWales Newborn Screening Laboratory, Department of Medical Biochemistry, Immunology & Toxicology, University Hospital of Wales, Cardiff CF14 4XW, UK.ORCID 0000-0002-3592-2254
James R BonhamClinical Chemistry, Sheffield Children's NHSFT, Sheffield S10 2TH, UK.ORCID 0009-0004-9485-6754
Christine CavanaghNHS England, Wellington House, London SE1 8UG, UK.
Margaret BirchHealth Protection & Screening Services, Public Health Wales, Cardiff CF10 4BZ, UK.
Caroline GriffithBiochemical Genetics, Specialist Laboratory Medicine, St James University Hospital, Leeds LS9 7TF, UK.
Lynette ShakespeareClinical Chemistry, Sheffield Children's NHSFT, Sheffield S10 2TH, UK.ORCID 0000-0001-9203-8169
Clare Le MasurierSouth West Newborn Screening and Metabolic Laboratory, Severn Pathology, Southmead Hospital, Bristol BS10 5NB, UK.
Claire ManfredoniaNewborn Screening Laboratory, Manchester University NHSFT, Manchester M13 9WL, UK.
Beverly HirdNewborn Screening Laboratory, Manchester University NHSFT, Manchester M13 9WL, UK.ORCID 0000-0002-7173-6862
Philippa GoddardNewborn Screening and Biochemical Genetics, Paediatric Laboratory Medicine, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK.
Sarah SmithScottish Newborn Screening Laboratory, Queen Elizabeth University Hospital, Glasgow G51 4TF, UK.
Laura WainwrightBlood Sciences, Portsmouth Hospitals Trust, Portsmouth PO6 3LY, UK.
Rachel S CarlingBiochemical Sciences, Synnovis, Guys & St Thomas' NHSFT, London SE1 7EH, UK.ORCID 0000-0003-1988-3088
Jennifer CundickRegional Newborn Screening Laboratory, Royal Victoria Hospital, Belfast BT12 6BA, UK.
Fiona JenkinsonNewborn Screening, Blood Sciences, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK.
Catherine CollingwoodBiochemistry Department, Alder Hey Children's NHS Foundation Trust, Liverpool L12 2AP, UK.
Nick FlynnBiochemical Genetics Unit, Cambridge University Hospitals NHSFT, Cambridge CB2 0QQ, UK.ORCID 0000-0003-3613-5890
Nazia TajOxford Screening Laboratory, Clinical Biochemistry, Oxford University Hospitals NHSFT, Oxford OX3 9DU, UK.
Mehdi MirzazadehSouth West Thames Newborn Screening, Epsom & St Helier Hospitals, Carshalton SM5 1AA, UK.ORCID 0000-0001-9068-3535
Tejswurree RamgoolamDepartment of Chemical Pathology, Great Ormond Street Hospital for Children, London WC1N 3JH, UK.
Liz RobinsonNHS England, Wellington House, London SE1 8UG, UK.
Amy HeadleyNHS England, Wellington House, London SE1 8UG, UK.
Tessa MorganNHS England, Wellington House, London SE1 8UG, UK.
David EllimanNHS England, Wellington House, London SE1 8UG, UK.
Lesley TetlowNewborn Screening Laboratory, Manchester University NHSFT, Manchester M13 9WL, UK.ORCID 0009-0005-6536-6534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2015, U.K. newborn screening (NBS) laboratory guidelines were introduced to standardize dried blood spot (DBS) specimen quality acceptance and specify a minimum acceptable DBS diameter of ≥7 mm. The UK 'acceptable' avoidable repeat rate (AVRR) is ≤2%. To assess inter-laboratory variability in specimen acceptance/rejection, two sets of colored scanned images (

Indexed as

avoidable repeat rateblood spot qualitydried blood spotsexternal quality assessmentfilter paperspecimen collectionspecimen collection device

Identifiers

PMID39311362
PMCPMC11417764

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.