Evidence map›Paper›PMID 39311299›Full record

ArticleClinics and practice2024

Characteristics, Management, and Outcomes of Acute Life-Threatening Asthma in Adult Intensive Care.

Adam J R Watson, Thomas Roe, Oliver Arscott, Charlotte Thomas, James Ward, Ryan Beecham, David Browning, Kordo Saeed, Ahilanandan Dushianthan

Abstract read
In one paragraph

Article in Clinics and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adam J R WatsonGeneral Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.ORCID 0000-0001-9178-4872
Thomas RoeGeneral Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.ORCID 0000-0002-5538-6719
Oliver ArscottGeneral Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.ORCID 0000-0003-1386-1259
Charlotte ThomasGeneral Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.ORCID 0000-0002-5028-5898
James WardGeneral Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Ryan BeechamGeneral Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
David BrowningDepartment of Infection, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Kordo SaeedClinical & Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.ORCID 0000-0003-0123-0302
Ahilanandan DushianthanGeneral Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.ORCID 0000-0002-0165-3359

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited evidence regarding the management of acute life-threatening asthma in intensive care units (ICUs), and few guidelines have details on this. We aimed to describe the characteristics, management, and outcomes of adults with life-threatening asthma requiring ICU admission.

methodsIn this single-centre retrospective observational study, we included consecutive adults with acute asthma requiring ICU admission between 1 January 2016 and 31 December 2023. Our primary outcome was requirement for invasive mechanical ventilation (IMV).

resultsWe included 100 patients (median age 42.5 years, 67% female). The median pH, PaCO

conclusionsOur data highlight key characteristics which may be risk factors for acute asthma requiring ICU admission and suggest that pH, PaCO

Indexed as

asthmaintensive care unitlife-threateningnear fatalventilation

Identifiers

PMID39311299
PMCPMC11417819

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.