ReviewInternational journal of physiology, pathophysiology and pharmacology2024
Extracellular vesicles and their therapeutic applications: a review article (part 2).
Review in International journal of physiology, pathophysiology and pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- NAMPT overexpression enhances the regenerative potential of mesenchymal stromal cell-derived extracellular vesicles in experimental AKI.Stem cell research & therapy · 2026Article
- Evaluating the electrocardiographic abnormalities in traumatic brain injury: prevalence, severity correlation, and outcome prediction.International journal of burns and trauma · 2026Review
- Cardiac biomarkers in acute burn injury: a systematic review of diagnostic and prognostic utility.International journal of burns and trauma · 2026Review
- Advancing cardiac tumor diagnosis: evaluatingAmerican journal of cardiovascular disease · 2026Review
- A Deep Learning Approach for Tracking Colorectal Cancer-Derived Extracellular Vesicles in Colon and Lung Models.ACS biomaterials science & engineering · 2025Article
- The use of radiopharmaceuticals in targeted cancer therapy: a narrative review.International journal of physiology, pathophysiology and pharmacology · 2025Review
- Artificial intelligence in automated detection of lung nodules: a narrative review.International journal of physiology, pathophysiology and pharmacology · 2025Review
- Advances in nanotechnology for targeted drug delivery in neurodegenerative diseases.American journal of neurodegenerative disease · 2025Review
- Cardiac magnetic resonance imaging in myocardial infarction with non-obstructed coronary arteries: diagnostic and prognostic value.American journal of cardiovascular disease · 2025Review
- Ischemic cardiomyopathy in a 43-year-old male with stroke during admission: the role of chronic amphetamine-dextroamphetamine use.International journal of physiology, pathophysiology and pharmacology · 2025Article
- Diagnostic challenges in cardiac amyloidosis: a case report of negative initial endomyocardial biopsy.International journal of physiology, pathophysiology and pharmacology · 2025Article
- Comparative risk of osteoporotic fractures with direct oral anticoagulants versus vitamin K antagonists in atrial fibrillation patients: a systematic review.International journal of burns and trauma · 2025Review
- Evaluation of the success rate of the semi-sitting position compared with the supine position in the emergency intubation of traumatic patients.International journal of burns and trauma · 2025Article
- Evaluating the efficacy of precise platelet-rich plasma injection in grade II meniscus tears.International journal of burns and trauma · 2025Article
- The zero calcium score paradox and multivessel obstructive disease: a case report of a patient with zero CAC score.American journal of cardiovascular disease · 2025Article
- The role of nuclear medicine in neurodegenerative diseases: a narrative review.American journal of neurodegenerative disease · 2025Review
- A review of the use of oral anticoagulants in individuals with atrial fibrillation who had experienced intracranial hemorrhage in the past.International journal of physiology, pathophysiology and pharmacology · 2025Review
- Tuberculous spondylodiscitis with ureteral involvement: a rare case report.American journal of clinical and experimental urology · 2025Article
- Determining the normal range of the dimensions and volume of the pituitary gland of children using a 3D magnetic resonance imaging (MRI) protocol in Imam Hossein Hospital of Isfahan in 2021 to 2024.American journal of neurodegenerative disease · 2025Article
- Safety and effectiveness of micropigmentation skin grafting using the Meek method.International journal of burns and trauma · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extracellular vesicles (EVs) have emerged as a fascinating area of research in molecular biology, with diverse therapeutic applications. These small membrane-bound structures, released by cells into the extracellular space, play a crucial role in intercellular communication and hold great potential for advancing medical treatments. The aim of this study is to have a narrative review on the use and therapeutic applications of EVs. Their unique characteristics, including stability, biocompatibility, and the ability to traverse biological barriers, make them promising tools for targeted drug delivery. By engineering EVs to encapsulate specific cargo molecules, such as therapeutic proteins, small interfering RNA (siRNA), or anti-cancer drugs, researchers can enhance drug stability and improve targeted delivery to desired cells or tissues. This approach can minimize off-target effects and improve therapeutic efficacy. Based on our literature search, we found that EVs can be used as biomarkers to predict diseases. Although much progress has been made in understanding the biology and function of exosomes, there are still unanswered questions that require further research. This includes identifying appropriate and safe techniques for producing exosomes in large quantities, determining which types of cells are suitable for exosome donor cells for therapeutic purposes, and investigating the safety of exosomes in human studies. Overall, the use of exosomes in clinical therapeutic applications requires a strong understanding of molecular signaling cascades and exosome profiles, as well as the specificity and sensitivity of biomarker and drug delivery methods.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.