Evidence map›Paper›PMID 39310711›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2024

The Relative Risk of COVID-19 in Solid Organ Transplant Recipients Over Waves of the Pandemic.

Amanda J Vinson, Alfred J Anzalone, Makayla Schissel, Ran Dai, Gaurav Agarwal, Stephen B Lee, Amy Olex, Roslyn B Mannon

Abstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amanda J VinsonDivision of Nephrology, Department of Medicine, Dalhousie University, Halifax, NS, Canada.
Alfred J AnzaloneDepartment of Biostatistics, University of Nebraska Medical Center, Omaha, NE, United States.
Makayla SchisselDepartment of Biostatistics, University of Nebraska Medical Center, Omaha, NE, United States.
Ran DaiDepartment of Biostatistics, University of Nebraska Medical Center, Omaha, NE, United States.
Gaurav AgarwalDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Stephen B LeeDivision of Infectious Diseases (Regina), University of Saskatchewan, Saskatoon, SK, Canada.
Amy OlexDepartment of Biostatistics, Virginia Commonwealth University, Virginia, United States.
Roslyn B MannonDivision of Nephology, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI RIZZO, MATTHEW · 2016 to 2025
$42.8M
CD2H - The National COVID Cohort Collaborative (N3C) IDeA CTR CollaborationU24TR002306 · NCATS · UNIVERSITY OF COLORADO DENVER · PI CHUTE, CHRISTOPHER G, EICHMANN, DAVID A. · 2017 to 2021
$28.9M
Wright Regional Center for Clinical and Translational ScienceUM1TR004360 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI FREDERICK Gerard MOELLER · 2023 to 2026
$16.3M
NCATS NIH HHS U24 TR002306NCATS NIH HHS UM1 TR004360NIGMS NIH HHS U54 GM104942NIGMS NIH HHS U54 GM115458
6 · The paper itself

Abstract

Solid organ transplant recipients (SOTR) are at increased risk from COVID-19. Over time, the absolute risk of adverse outcomes after COVID-19 has decreased in both the non-immunosuppressed/immunocompromised (non-ISC) general population, and amongst SOTR. Using the N3C, we examined the absolute risk of mortality, major adverse renal or cardiac events, and hospitalization after COVID-19 diagnosis amongst non-ISC and SOTR populations over five waves of the pandemic (Wave 1: Ancestral COVID; Wave 2: Alpha; Wave 3: Delta; Wave 4: Omicron; Wave 5: Omicron). Within each wave, we determined the relative risk of each outcome for SOTR versus the non-ISC population based on crude event rates, and then used multivariable cox proportional hazards models and logistic regression to determine the adjusted risk of each outcome based on SOT status. Throughout the pandemic, including during the Omicron wave (Wave 5), SOTR were at greater absolute risk for each outcome than non-ISC patients (

Indexed as

COVID-19HospitalizationOrgan TransplantationTransplant RecipientsAdultAgedFemaleHumansImmunocompromised HostMaleMiddle AgedPandemicsProportional Hazards ModelsRisk FactorsSARS-CoV-2COVID-19outcomespandemicrelative risksSars-CoV-2transplantvariant strainwaves

Identifiers

PMID39310711
PMCPMC11413870

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.