Evidence map›Paper›PMID 39310646›Full record

ArticleCureus2024

Secondary Metabolites of Halobacillus sp.: Antimicrobial and Antioxidant Activity, Biological Compatibility, and Gas Chromatography-Mass Spectrometry (GC-MS) Analysis.

Aayisha Aathila Saleem, Gayathri Balakrishnan, Manivannan Nandhagopal

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aayisha Aathila SaleemBiocontrol and Microbial Products Lab, Department of Microbiology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Gayathri BalakrishnanBiocontrol and Microbial Products Lab, Department of Microbiology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Manivannan NandhagopalBiocontrol and Microbial Products Lab, Department of Microbiology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The rise of infectious diseases and the emergence of resistant pathogens pose significant challenges to human health. In response to this global threat, researchers are exploring novel sources of bioactive compounds for effective antimicrobial therapies. One avenue of investigation is the study of halophilic bacteria and their secondary metabolites. These bacteria thrive under extreme conditions and produce valuable bioactive metabolites, which have the potential for therapeutic applications. Methods In this study, the potent bacterial cultures obtained from the Payanur salt pan, Tamil Nadu, were analyzed for the antimicrobial activity of their metabolites. The secondary metabolites were obtained from the halophilic bacteria by culturing the bacteria in 8% NaCl. The resultant secondary metabolites produced were extracted using ethyl acetate and their antimicrobial property was studied using the well diffusion method. The minimum inhibitory concentration (MIC) of these metabolites against five clinical pathogens, namely,

Indexed as

antimicrobial activitybio-compatibilitydurg discoveryhalophilic bacteriasecondary metabolites

Identifiers

PMID39310646
PMCPMC11414998

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.