Evidence map›Paper›PMID 39310403›Full record

ArticleCureus2024

CT-Guided Online Adaptive Radiotherapy Delivered via Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) for a Bulky Thoracic and Abdominal Mass in Oligometastatic Renal Cell Carcinoma.

Ari A Kassardjian, Colton Ladbury, Borna Maraghechi, Chengyu Shi, Tyler Watkins, An Liu, Kevin Tsai, Terence Williams, Yun Rose Li, Savita Dandapani and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ari A KassardjianRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
Colton LadburyRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
Borna MaraghechiRadiation Oncology, City of Hope Orange County Lennar Foundation Cancer Center, Irvine, USA.
Chengyu ShiRadiation Oncology, City of Hope Orange County Lennar Foundation Cancer Center, Irvine, USA.
Tyler WatkinsRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
An LiuRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
Kevin TsaiRadiation Oncology, City of Hope Orange County Lennar Foundation Cancer Center, Irvine, USA.
Terence WilliamsRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
Yun Rose LiRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
Savita DandapaniRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
Amanda SchwerRadiation Oncology, City of Hope Orange County Lennar Foundation Cancer Center, Irvine, USA.
Percy LeeRadiation Oncology, City of Hope Orange County Lennar Foundation Cancer Center, Irvine, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the context of oligometastatic renal cell carcinoma (RCC), local treatment with stereotactic body radiotherapy (SBRT) may improve oncologic outcomes. However, the location and size can often pose a technical challenge in standard SBRT delivery, and the dose is potentially limited by nearby organs at risk (OARs). Online adaptive radiotherapy (oART) improves radiation delivery by personalizing high-dose fractions to account for daily stochastic variations in patient anatomy or setup. The oART process aims to maximize tumor control and enhances precision by tailoring to a more accurate representation of a patient in near-real time. The proceeding re-optimization can mitigate the uncertainty inherent in the traditional radiation delivery workflow and precludes the need for larger margins that account for anatomical variations and setup errors. Here, we describe a case of oligometastatic RCC with a bulky (>300 cm

Indexed as

adaptive radiation therapyethosperipheral lung sbrtrenal cell carcinoma (rcc)sbrt (stereotactic body radiotherapy)

Identifiers

PMID39310403
PMCPMC11416129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.