Evidence map›Paper›PMID 39310373›Full record

ReviewThe World Allergy Organization journal2024

Food allergies in older people: An emerging health problem.

Domenico Azzolino, Lara Verdi, Simone Perna, Ivan Baldassari, Matteo Cesari, Tiziano Lucchi

Abstract readReview
In one paragraph

Review in The World Allergy Organization journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Age-dependent differences in anaphylaxis: elderly population.Current opinion in allergy and clinical immunology · 2025
    Review
  7. Endogenous retroelements promote tolerance to dietary antigens.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Characteristics and Outcomes of Anaphylaxis in Emergency Department Visits Among Older Adults.The journal of allergy and clinical immunology. In practice · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Domenico AzzolinoGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
Lara VerdiSpecialization School in Geriatrics, University of Milan, Milan, Italy.
Simone PernaDepartment of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, University of Milan, Milan, Italy.
Ivan BaldassariDepartment of Research, Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Matteo CesariDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Tiziano LucchiGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of food allergy (FA) is steadily increasing worldwide. Literature about FA in older people is very scarce since this is predominantly considered as a pediatric condition. However, FA can persist and/or develop across the life course. Given the growing increase in prevalence as well as their persistence, it can be expected that FA will soon represent an important issue in older people. Several age-related factors may potentially mask FA symptoms and/or mediate them in older people. These include mechanisms related to immune senescence, inflammation, and changes in gastrointestinal function as well as micronutrient deficiencies and the use of multiple medications. A multidimensional approach, taking into account the complexity in older people, it is thus important in the evaluation and management of FA during aging. The main and safest strategy in the management of FA is the allergen avoidance since their ingestion may lead to reactions ranging from mild to life-threatening. However, food restrictions should be carefully evaluated, especially in older people, for the risk of nutritional deficiencies and undernutrition.

Indexed as

AgingFood hypersensitivityFrailtyMalnutritionOral allergy syndrome

Identifiers

PMID39310373
PMCPMC11416488

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.