Evidence map›Paper›PMID 39310344›Full record

ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2024

Patient Perspectives on Evolving Diverticulitis Treatment: An Assessment of Patient Willingness to Enroll in a Randomized Controlled Trial.

Annie Altman-Merino, Kemberlee Bonnet, David Schlundt, Jesse Wrenn, Wesley H Self, Elisa J Gordon, Alexander T Hawkins

Abstract read
In one paragraph

Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Annie Altman-MerinoFrom the Department of School of Medicine, Vanderbilt University, Nashville, TN.
Kemberlee BonnetDepartment of Psychology, Vanderbilt University, Nashville, TN.
David SchlundtDepartment of Psychology, Vanderbilt University, Nashville, TN.
Jesse WrennDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN.
Wesley H SelfDepartment of Emergency Medicine, Vanderbilt University Medical Center, Vanderbilt Institute for Clinical and Translational Research, Nashville, TN.
Elisa J GordonDepartment of Surgery, and Center for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN.
Alexander T HawkinsDepartment of Surgery, Section of Colon & Rectal Surgery, Vanderbilt University Medical Center, Nashville, TN.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Vanderbilt Interdisciplinary Hospital-Based Systems of Care Research and Training ProgrAm (VISTA)T32HL170986 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SUNIL KRIPALANI, ALAN B STORROW · 2024 to 2026
$1.3M
Novel Assessment of the Role of Surgery in Recurrent DiverticulitisK23DK118192 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HAWKINS, ALEXANDER THARRINGTON · 2018 to 2022
$788k
NCATS NIH HHS UL1 TR002243NHLBI NIH HHS T32 HL170986NIDDK NIH HHS K23 DK118192
6 · The paper itself

Abstract

Objective: The objective of the study was to assess patients' attitudes regarding participation in a randomized trial of antibiotics Background: Despite evidence that antibiotics may not be necessary to treat acute uncomplicated diverticulitis, they remain the mainstay of treatment in the United States. A randomized trial in the United States evaluating antibiotic effectiveness could accelerate the implementation of antibiotic-free treatment, but providers maintain concerns that patients may be unwilling to participate. Methods: This mixed-methods study conducted semi-structured interviews of patients presenting to a quaternary care emergency department with acute diverticulitis and a web-based survey of a larger cohort. The interviews assessed patients' experiences with diverticulitis and perceptions of participation in a trial comparing antibiotics versus placebo. The survey quantified patients' willingness to participate in such a study and the relative importance of factors influencing the process. Results: Thirteen patients completed an interview. Reasons to participate included a desire to help others or contribute to scientific knowledge. Doubts about the efficacy of observation as a treatment method were the main barrier to participation. In a survey of 218 subjects, 62% of respondents reported willingness to participate in a randomized clinical trial. "What my doctor thinks," followed by "What I have experienced in the past" were the most important decision-making factors. Conclusion: Patients with acute uncomplicated diverticulitis maintain complex and varying perceptions of antibiotic use. Most surveyed patients would be willing to participate in a trial of antibiotics

Identifiers

PMID39310344
PMCPMC11415118

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.