Evidence map›Paper›PMID 39310244›Full record

ArticleWorld journal of methodology2024

Anticoagulant use before COVID-19 diagnosis prevent COVID-19 associated acute venous thromboembolism or not: A systematic review and meta-analysis.

Kinza Iqbal, Akshat Banga, Taha Bin Arif, Sawai Singh Rathore, Abhishek Bhurwal, Syeda Kisa Batool Naqvi, Muhammad Mehdi, Pankaj Kumar, Mitali Madhu Salklan, Ayman Iqbal and 6 more

Abstract read
In one paragraph

Article in World journal of methodology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kinza IqbalDepartment of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Akshat BangaDepartment of Internal Medicine, Sawai Man Singh Medical College, Jaipur 302004, India.
Taha Bin ArifDepartment of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Sawai Singh RathoreDepartment of Internal Medicine, Dr. Sampurnanand Medical College, Jodhpur 342003, Rajasthan, India.
Abhishek BhurwalDepartment of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson School of Medicine, New Brunswick, NJ 08901, United States.
Syeda Kisa Batool NaqviDepartment of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Muhammad MehdiDepartment of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Pankaj KumarDepartment of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Mitali Madhu SalklanDepartment of Internal Medicine, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak 124001, Haryana, India.
Ayman IqbalDepartment of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Jawad AhmedDepartment of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Nikhil SharmaDepartment of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, United States.
Amos LalDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, United States.
Rahul KashyapDepartment of Research, Wellspan Health, York, PA 17403, United States.
Vikas BansalDepartment of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, United States. bansal.vikas@mayo.edu.
Juan Pablo DomecqDepartment of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoagulopathy and thromboembolic events are associated with poor outcomes in coronavirus disease 2019 (COVID-19) patients. There is conflicting evidence on the effects of chronic anticoagulation on mortality and severity of COVID-19 disease.

aimTo summarize the body of evidence on the effects of pre-hospital anticoagulation on outcomes in COVID-19 patients.

methodsA Literature search was performed on LitCovid PubMed, WHO, and Scopus databases from inception (December 2019) till June 2023 for original studies reporting an association between prior use of anticoagulants and patient outcomes in adults with COVID-19. The primary outcome was the risk of thromboembolic events in COVID-19 patients taking anticoagulants. Secondary outcomes included COVID-19 disease severity, in terms of intensive care unit admission or invasive mechanical ventilation/intubation requirement in patients hospitalized with COVID-19 infection, and mortality. The random effects models were used to calculate crude and adjusted odds ratios (aORs) with 95% confidence intervals (95%CIs).

resultsForty-six observational studies met our inclusion criteria. The unadjusted analysis found no association between prior anticoagulation and thromboembolic event risk [

conclusionPrehospital anticoagulation was not significantly associated with reduced risk of thromboembolic events, improved survival, and lower disease severity in COVID-19 patients.

Indexed as

Chronic anticoagulationCOVID-19MortalityPrehospital anticoagulationPrior anticoagulationSeverityThromboembolic events

Identifiers

PMID39310244
PMCPMC11230074

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.