Evidence map›Paper›PMID 39310055›Full record

ReviewJournal of intensive medicine2024

Glucocorticoid therapy for acute respiratory distress syndrome: Current concepts.

Yuanrui Zhao, Zhun Yao, Song Xu, Lan Yao, Zhui Yu

Abstract readReview
In one paragraph

Review in Journal of intensive medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuanrui ZhaoDepartment of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Zhun YaoDepartment of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Song XuDepartment of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Lan YaoDepartment of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Zhui YuDepartment of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS), a fatal critical disease, is induced by various insults. ARDS represents a major global public health burden, and the management of ARDS continues to challenge healthcare systems globally, especially during the pandemic of the coronavirus disease 2019 (COVID-19). There remains no confirmed specific pharmacotherapy for ARDS, despite advances in understanding its pathophysiology. Debate continues about the potential role of glucocorticoids (GCs) as a promising ARDS clinical therapy. Questions regarding GC agent, dose, and duration in patients with ARDS need to be answered, because of substantial variations in GC administration regimens across studies. ARDS heterogeneity likely affects the therapeutic actions of exogenous GCs. This review includes progress in determining the GC mechanisms of action and clinical applications in ARDS, especially during the COVID-19 pandemic.

Indexed as

Acute respiratory distress syndromeClinical trialsCOVID-19GlucocorticoidsHeterogeneitySteroids

Identifiers

PMID39310055
PMCPMC11411438

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.