Evidence map›Paper›PMID 39309600›Full record

ReviewFrontiers in cardiovascular medicine2024

Chronic thromboembolic pulmonary hypertension: the diagnostic assessment.

Beatrice Simeone, Enrico Maggio, Leonardo Schirone, Erica Rocco, Gianmarco Sarto, Luigi Spadafora, Marco Bernardi, Luca D' Ambrosio, Maurizio Forte, Daniele Vecchio and 3 more

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Imaging in chronic thromboembolic pulmonary hypertension: review of the current literature.Diagnostic and interventional radiology (Ankara, Turkey) · 2026
    Review
  4. Catheter-directed thrombectomy in acute pulmonary embolism and angiographic signs of chronic thromboembolic pulmonary disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Beatrice Simeone *Department of Cardiology, ICOT Istituto Marco Pasquali, Latina, Italy.
Enrico Maggio *Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.
Leonardo Schirone *Department of Angiocardioneurology, IRCCS Neuromed, Pozzilli, Italy.
Erica RoccoDepartment of Cardiology, ICOT Istituto Marco Pasquali, Latina, Italy.
Gianmarco SartoDepartment of Cardiology, ICOT Istituto Marco Pasquali, Latina, Italy.
Luigi SpadaforaDepartment of Cardiology, ICOT Istituto Marco Pasquali, Latina, Italy.
Marco BernardiDepartment of Cardiology, ICOT Istituto Marco Pasquali, Latina, Italy.
Luca D' AmbrosioDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.
Maurizio ForteDepartment of Angiocardioneurology, IRCCS Neuromed, Pozzilli, Italy.
Daniele VecchioDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.
Valentina ValentiDepartment of Cardiology, Santa Maria Goretti Hospital, Latina, Italy.
Sebastiano SciarrettaDepartment of Angiocardioneurology, IRCCS Neuromed, Pozzilli, Italy.
Carmine Dario VizzaDepartment of Cardiovascular and Respiratory Sciences, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) presents a significant diagnostic challenge due to its complex and often nonspecific clinical manifestations. This review outlines a comprehensive approach to the diagnostic assessment of CTEPH, emphasizing the importance of a high index of suspicion in patients with unexplained dyspnea or persistent symptoms post-acute pulmonary embolism. We discuss the pivotal role of multimodal imaging, including echocardiography, ventilation/perfusion scans, CT pulmonary angiography, and magnetic resonance imaging, in the identification and confirmation of CTEPH. Furthermore, the review highlights the essential function of right heart catheterization in validating the hemodynamic parameters indicative of CTEPH, establishing its definitive diagnosis. Advances in diagnostic technologies and the integration of a multidisciplinary approach are critical for the timely and accurate diagnosis of CTEPH, facilitating early therapeutic intervention and improving patient outcomes. This manuscript aims to equip clinicians with the knowledge and tools necessary for the efficient diagnostic workflow of CTEPH, promoting awareness and understanding of this potentially treatable cause of pulmonary hypertension.

Indexed as

chronic thromboembolic pulmonary hypertension (CTEPH)diagnosisnarrative reviewpulmonary hypertensionrare disease

Identifiers

PMID39309600
PMCPMC11412851

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.