Smoking is a predominant risk factor for coronary artery disease among Indians.

Smoking has emerged as a predominant risk factor for coronary artery disease (CAD) in India, contributing significantly to the country's rising cardiovascular morbidity and mortality rates. The adverse effects of tobacco on cardiovascular health are well-documented, exacerbating a public health challenge in a nation with a high prevalence of smoking. Therefore, it is of interest to analyse the impact of smoking on the incidence and progression of coronary artery disease among the Indian population, emphasizing the need for targeted public health interventions to mitigate this risk factor. We included 1000 adults were enrolled from January to July 2023. The group comprised 500 CAD patients (cases) and 500 individuals without CAD (controls). We gathered information on demographics, smoking habits & other CAD risk factors. To assess the relationships between smoking, CAD, and other variables, we utilized multivariate logistic regression. The analysis revealed that current smokers had a substantially increased likelihood of CAD, with an unadjusted odds ratio (OR) of 3.20 (95% CI: 2.45-4.18), compared to non-smokers. This association remained significant even after adjusting for confounders, with an adjusted OR of 2.80 (95% CI: 2.10-3.75). The study confirms smoking as a critical, Adaptable risk element for CAD, independently increasing the risk of the disease. Smoking significantly elevates the risk of developing coronary artery disease among Indians. Comprehensive anti-smoking campaigns and stringent tobacco control policies are imperative to reduce the burden of CAD. Public health strategies must focus on awareness, prevention, and cessation support to combat this major health threat effectively.