Evidence map›Paper›PMID 39309139›Full record

ArticleFrontiers in nutrition2024

Ultra-processed foods intake and sex hormone levels among children and adolescents aged 6-19 years: a cross-sectional study.

Hao Zhao, Wei Gui, Shangtao Liu, Fangyu Zhao, Wenyan Fan, Fangyuan Jing, Chuan Sun

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Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Hao ZhaoDepartment of Preventive Medicine, School of Basic Medical Sciences, Jiujiang University, Jiujiang, China.
Wei GuiDepartment of Pediatric, The Affiliated Hospital of Jiujiang University, Jiujiang, China.
Shangtao LiuDepartment of Preventive Medicine, School of Basic Medical Sciences, Jiujiang University, Jiujiang, China.
Fangyu ZhaoDepartment of Preventive Medicine, School of Basic Medical Sciences, Jiujiang University, Jiujiang, China.
Wenyan FanDepartment of Preventive Medicine, School of Basic Medical Sciences, Jiujiang University, Jiujiang, China.
Fangyuan JingDepartment of Molecular Mechanisms of Chronic Diseases, Shulan International Medical College, Zhejiang Shuren University, Hangzhou, China.
Chuan SunZhejiang Key Laboratory of Geriatrics and Geriatrics Institute of Zhejiang Province, Zhejiang Hospital, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sex hormones are crucial for the development of children and adolescents. The increasing consumption of ultra-processed foods (UPFs) among children and adolescents in the United States (US) has raised concerns about their potential impact on health, including hormonal balance. Methods: Data from 3,354 participants aged 6-19 years from the NHANES 2013-2016 were analyzed. UPF intake was categorized using the NOVA food classification system, and the percentage of total daily energy intake from UPFs was calculated. The serum levels of total testosterone (TT), sex hormone-binding globulin (SHBG), and estradiol (E2) were measured. The free androgen index (FAI) and TT/E2 ratio were calculated to estimate bioavailable testosterone levels and the balance between androgens and estrogens, respectively. Multiple linear regression models, adjusted for potential confounders, estimated the associations. Results: Our results showed that higher intake of UPFs was marginally associated with decreased serum SHBG levels (quartile (Q) 2 vs. Q1: Conclusion: Higher UPF consumption is associated with increased FAI in adolescents, particularly in girls, indicating higher bioavailable testosterone levels. Future studies should validate these findings with direct free testosterone measurements and more precise dietary intake assessments.

Indexed as

adolescentchildcross-sectionalsex hormonesultra-processed foods

Identifiers

PMID39309139
PMCPMC11412839

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.