Evidence map›Paper›PMID 39309107›Full record

ArticleFrontiers in endocrinology2024

The association of triglyceride-glucose index and combined obesity indicators with chest pain and risk of cardiovascular disease in American population with pre-diabetes or diabetes.

Dongze Zheng, Jiamiao Cai, Sifan Xu, Shiyan Jiang, Chenlin Li, Bin Wang

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dongze ZhengDepartment of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Jiamiao CaiDepartment of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Sifan XuDepartment of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
Shiyan JiangDepartment of Nephrology, Jieyang People's Hospital, Jieyang, Guangdong, China.
Chenlin LiDepartment of Cardiology, Jieyang People's Hospital, Jieyang, Guangdong, China.
Bin WangDepartment of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To investigate the correlation of the triglyceride-glucose (TyG) index and its combined obesity indicators with chest pain and cardiovascular disease (CVD) in the pre-diabetes and diabetes population. Methods: This cross-sectional investigation encompassed 6488 participants with diabetes and pre-diabetes who participated in the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2016. The association of the TyG and combined obesity index with chest pain and CVD was investigated using weighted logistic regression models and restricted cubic spline (RCS) analysis. The receiver operating characteristic (ROC) curve analysis was performed to compare different indicators. Results: In multivariate logistic regression fully adjusted for confounding variables, our analyses revealed significant associations between TyG, TyG-BMI, TyG-WC, and TyG-WHtR and chest pain, with adjusted ORs (95% CI) of 1.21 (1.05, 1.39), 1.06 (1.01, 1.11), 1.08 (1.04, 1.14), and 1.27 (1.08, 1.48), respectively. For total-CVD, the adjusted ORs (95% CI) were 1.32 (1.08, 1.61), 1.10 (1.03, 1.17), 1.13 (1.06, 1.19), and 1.63 (1.35, 1.97), respectively, among which TyG, TyG-WC, and TyG-WHtR present curvilinear associations in RCS analysis (all Conclusion: There are significant associations of TyG and its related indicators with chest pain and total-CVD among the pathoglycemia population. TyG-WC and TyG-WHtR demonstrated superior predictive capability for the incidence of cardiovascular events.

Indexed as

Blood GlucoseCardiovascular DiseasesChest PainNutrition SurveysObesityPrediabetic StateTriglyceridesAdultAgedCross-Sectional StudiesDiabetes MellitusFemaleHumansMaleMiddle AgedRisk FactorsBlood GlucoseTriglyceridescardiovascular diseasechest paindiabetesobesitypre-diabetestriglyceride-glucose index

Identifiers

PMID39309107
PMCPMC11412814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.