ArticleTremor and other hyperkinetic movements (New York, N.Y.)2024
Directional Stimulus-Evoked Pallidal Electrophysiology in Primary Dystonia.
Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Clinical and Genetic Spectrum of ANO3-Related Dystonia with Treatment Responses in a Chinese Cohort.Genes · 2026Article
- Pallidal Evoked Resonant Neural Activity as a Candidate Biomarker for Deep Brain Stimulation in Dystonia.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Deep brain stimulation-induced local evoked potentials outperform spectral features in spatial and clinical STN mapping.Journal of neural engineering · 2025Article
- Paired Deep Brain Stimuli Elicit Short-Term Facilitation in Globus Pallidus Interna and Subthalamic Nucleus.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Deep brain stimulation-induced local evoked potentials outperform spectral features in spatial and clinical STN mapping.medRxiv : the preprint server for health sciences · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Background: Deep brain stimulation for dystonia improves motor symptoms but variable and delayed responses challenge patient selection, targeting, and device programming. Case Report: Here we studied intracranial electrophysiology in a patient with primary dystonia and observed evoked resonant neural activity (ERNA) in the globus pallidus interna. These local stimulus-evoked potentials displayed refractory periods and paired-pulse facilitation at clinically relevant interstimulus intervals. Sensing from directional DBS contacts localized ERNA to an effective stimulation site in the ventral posterolateral portion of the pallidum. Discussion: To the best of our knowledge, this is the first observation of ERNA in the globus pallidus interna in a patient with primary dystonia. Stimulus-evoked activity could eventually guide both directional and adaptive stimulation for dystonia and other complex neuropsychiatric disorders.
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Registered trials
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