Evidence map›Paper›PMID 39308936›Full record

ArticleAnnals of case reports2024

The Impact of Caregiver/Care-Receiver Co-Treatment in a Therapeutic Lifestyle Intervention for Chronic Spinal Cord Injury: A Comparative Case Series.

G E Bigford, D A Lehmann, A J Mendez, M S Nash

Registry-linked trialAbstract read
In one paragraph

Article in Annals of case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02853149 (A Lifestyle Intervention Targeting Enhanced Health and Function for Persons With Chronic SCI in Caregiver/Care-Receiver Relationships), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02853149 nacompletednot on this map

A Lifestyle Intervention Targeting Enhanced Health and Function for Persons With Chronic SCI in Caregiver/Care-Receiver Relationships: Effects of Caregiver Co-Treatment

TypeinterventionalSponsorUniversity of MiamiRan2016 to 2022Enrolled22ConditionsSpinal Cord Injury, Cardiovascular Diseases, ObesityArmsSpinal Cord Injury (SCI), Caregiver Intervention(CCC), Caregiver Control (CC)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

G E BigfordThe Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, USA.
D A LehmannThe Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, USA.
A J MendezThe Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, USA.
M S NashThe Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

ACL HHS 90DP0074
6 · The paper itself

Abstract

Introduction: This study is a prospective comparative case series analysing the differential impacts of a therapeutic lifestyle intervention (TLI) on individuals with spinal cord injury (SCI) and their caregivers. The primary objective was to assess changes across several health metrics predictive of cardio metabolic disease (CMD), fitness, and quality of life, in dyadic partners and between 2 separate cases. Case Presentation: SCI participants and their respective caregivers, forming 10 dyads, were included in the study. Dyads were randomly assigned to two distinct case scenarios: Case 1, where both dyadic partners received TLI; and Case 2, where only the SCI partner received the intervention. Each case series comprised five dyads. TLI constituted a rigorous 6-month program consisting of exercise, adherence to a Mediterranean diet, and behavioural support. Across cases, notable improvements were observed in body mass, and strength among SCI partners; and reductions in body mass and fasting glucose, and improved mental well-being was observed in caregiver partners. Dyadic interaction analysis found that insulin, HOMA, HDL, and mental health improvements in SCI were strongly linked to improvements in caregiver when both dyadic partners received TLI. Conclusion: We conclude that TLI co-treatment for dyadic partners, including exercise, nutrition, and behaviour modification, improves health outcomes related to CMD risks and quality of life in both populations. Trial Registration: ClinicalTrials.gov, ID: NCT02853149 Registered August 2, 2016.

Identifiers

PMID39308936
PMCPMC11414831

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