Evidence map›Paper›PMID 39308786›Full record

ArticleIJID regions2024

Trends in continuity of treatment among children and adolescents living with HIV in 14 districts in South Africa from 2018-2023: A retrospective program analysis.

Bridget Mugisa, Kathleen Kehoe, Tabisa Silere-Maqetseba, Hlamalani Mabasa, Rachel Golin, Joel Chehab, Alexandra Vrazo, Meena Srivastava

Abstract read
In one paragraph

Article in IJID regions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bridget MugisaBilateral Health Office, United States Agency for International Development, Pretoria, South Africa.
Kathleen KehoeBilateral Health Office, United States Agency for International Development, Pretoria, South Africa.
Tabisa Silere-MaqetsebaNational Department of Health, Pretoria, South Africa.
Hlamalani MabasaBilateral Health Office, United States Agency for International Development, Pretoria, South Africa.
Rachel GolinOffice of HIV/AIDS, United States Agency for International Development (USAID), Washington, United States of America.
Joel ChehabBilateral Health Office, United States Agency for International Development, Pretoria, South Africa.
Alexandra VrazoGlobal Health Training, Advisory, and Support Contract (GH-TASC), Credence Management Solutions LLC, supporting the Office of HIV/AIDS, United States Agency for International Development (USAID), Washington, United States of America.
Meena SrivastavaOffice of HIV/AIDS, United States Agency for International Development (USAID), Washington, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: UNAIDS estimates 152,984 children under 15 years living with HIV (C/ALHIV) by 2022 in South Africa. Monitoring the continuity of antiretroviral treatment remains challenging without electronic health records. We explored treatment cohort growth and interruption trends in 14-USAID-PEPFAR-supported districts. Methods: We reviewed data from 2018 to 2023. We triangulated this data with NAOMI HIV estimates. We used Tableau version 2023.2 for analysis to understand heterogeneity in outcomes. Results: HIV incidence halved from 4.3 per 1000 in 2017 to 2.5 per 1000 in 2022. HIV testing doubled: 188,371 in FY19Q1 to 399,708 in FY23Q4 while testing positivity declined from 3.3% to 0.7%. Linkage to treatment increased from 67% to 102%, viral suppression increased from 79% to 84%. C/ALHIV treatment cohort started at 82,897 in FY19Q1 and increased to 105,107 in FY20Q2. Subsequently, the cohort decreased to 79,288 in FY23Q4 despite 42,498 initiations and 62,256 returns. Conclusions: The C/ALHIV treatment and viral suppression increased substantially commensurate with expected trends. Subsequent cohort decline was aligned to vertical transmission reduction, HIV incidence decline, and expected aging. We highlight the inadequacy of the information systems to quantify losses. We underscore a need for resources to enhance program monitoring and interventions to address this gap.

Indexed as

AdolescentsContinuity of treatmentHealth information systemsPediatric HIV

Identifiers

PMID39308786
PMCPMC11416216

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.