Evidence map›Paper›PMID 39308784›Full record

ArticleIJID regions2024

Twenty-five years of Nipah outbreaks in Southeast Asia: A persistent threat to global health.

Sakirul Khan, Sheikh Mohammad Fazle Akbar, Mamun Al Mahtab, Md Nasir Uddin, Md Mamunur Rashid, Takaaki Yahiro, Takehiro Hashimoto, Kazunori Kimitsuki, Akira Nishizono

Abstract read
In one paragraph

Article in IJID regions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. Proteome conserved multi-epitope-based vaccine construct against Nipah virus.Naunyn-Schmiedeberg's archives of pharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sakirul KhanResearch Center for Global and Local Infectious Diseases, Oita University, Oita, Japan.
Sheikh Mohammad Fazle AkbarResearch Center for Global and Local Infectious Diseases, Oita University, Oita, Japan.
Mamun Al MahtabResearch Center for Global and Local Infectious Diseases, Oita University, Oita, Japan.
Md Nasir UddinInstitute of Public Health, Dhaka, Bangladesh.
Md Mamunur RashidBangladesh Institute of Tropical and Infectious Diseases, Chittagong, Bangladesh.
Takaaki YahiroResearch Center for Global and Local Infectious Diseases, Oita University, Oita, Japan.
Takehiro HashimotoDepartment of Microbiology, Faculty of Medicine, Oita University, Oita, Japan.
Kazunori KimitsukiResearch Center for Global and Local Infectious Diseases, Oita University, Oita, Japan.
Akira NishizonoResearch Center for Global and Local Infectious Diseases, Oita University, Oita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Nipah virus (NiV), a bat-borne zoonotic pathogen, poses persistent threats to global public health due to severe clinical manifestation and high case fatality rate (CFR). A critical examination of NiV outbreaks is essential for refining strategies and mitigating the impact of future infections. In this study, we provide a concise update on global NiV outbreaks that occurred during the past 25 years. Methods: In this geospatial study, we conducted an in-depth examination of the epidemiological characteristics of human NiV cases and deaths from 1998 to 2024 through multiple analyses of public data and official reports. Results: NiV emerged in 1998 in Malaysia during an outbreak among pig farmers. Since then, NiV outbreaks have been documented in five countries of South and Southeast Asia (Bangladesh, India, Malaysia, Philippines, and Singapore). As of May 2024, there have been 754 confirmed human NiV cases with 435 deaths (CFR: 58%) reported in these five countries. Bangladesh records the highest incidence (341 cases and 241 deaths; CFR: 71%) followed by Malaysia (283 cases and 109 deaths; CFR: 39%), India (102 cases and 74 deaths; CFR: 73%), the Philippines (17 cases and nine deaths; CFR: 53%), and Singapore (11 cases and one death; CFR: 9%). Conclusions: The clinical outcomes of NiV have been underscoring constant global public health threats as no effective therapies and vaccines are available. Strong global understandings, with an eye on developing vaccines and therapeutics, are required to minimize clinical outcomes and future threats of NiV.

Indexed as

Active surveillanceGlobal understandingHigh fatalityNipah outbreaksSoutheast AsiaVaccine and therapeutics

Identifiers

PMID39308784
PMCPMC11414670

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.