Evidence map›Paper›PMID 39308707›Full record

ArticleOpen veterinary journal2024

Immune response and safety of co-administered peste des petits ruminants, contagious caprine pleuropneumonia, sheep and goat pox, and Pasteurellosis vaccines in goats.

Takele Tesgera Hurisa, Takele Abayneh Tefera, Retta Negatu, Teshale Sori, Berecha Bayisa Deme, Mirtneh Akalu Yilma, Wondwossen Tolossa, Abinet Legesse, Ashetu Negewo, Wubet W/Medhin and 5 more

Abstract read
In one paragraph

Article in Open veterinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Takele Tesgera HurisaNational Veterinary Institute, Bishoftu, Ethiopia.
Takele Abayneh TeferaNational Veterinary Institute, Bishoftu, Ethiopia.
Retta NegatuNational Veterinary Institute, Bishoftu, Ethiopia.
Teshale SoriNational Veterinary Institute, Bishoftu, Ethiopia.
Berecha Bayisa DemeNational Veterinary Institute, Bishoftu, Ethiopia.
Mirtneh Akalu YilmaLuna Export Abattoir, Central Oromia, Ethiopia.
Wondwossen TolossaLuna Export Abattoir, Central Oromia, Ethiopia.
Abinet LegesseLuna Export Abattoir, Central Oromia, Ethiopia.
Ashetu NegewoLuna Export Abattoir, Central Oromia, Ethiopia.
Wubet W/MedhinLuna Export Abattoir, Central Oromia, Ethiopia.
Kedir SherefaLuna Export Abattoir, Central Oromia, Ethiopia.
Getu AyeleLuna Export Abattoir, Central Oromia, Ethiopia.
Adugna GeresuDepartment of Clinical Studies, Addis Ababa University College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia.
Eyob AssefaDepartment of Clinical Studies, Addis Ababa University College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia.
Dawit DuferaDepartment of Clinical Studies, Addis Ababa University College of Veterinary Medicine and Agriculture, Bishoftu, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infectious diseases such as peste des petits ruminants (PPRs), contagious caprine pleuropneumonia (CCPP), sheep and goat pox (SGPX), and pasteurellosis have considerable impacts on the optimal utilization of sheep and goat resources in Ethiopia. Immunization using multiple vaccines administered simultaneously has been suggested as a cost-effective and safe approach to controlling and preventing these diseases. Aim: The aim of this study was to assess the immunogenicity and safety of multiple vaccines administered simultaneously in goats. Methods: Sero-negative PPR, CCPP, SGPX, and Pasteurellosis goats were immunized with multiple vaccines. Goats vaccinated with a single vaccine against each disease served as a positive control. The immune response of the goats was assessed using serological tests, and any adverse effects were monitored. Results: The results of the present study showed that goats vaccinated with multiple vaccines exhibited a remarkable immune response against PPR, CCPP, and pasteurellosis. In contrast, they did not produce a protective immune response against sheep or goat pox. No adverse effects were observed with any of the vaccines. Conclusion: This study suggested that combined vaccines can be effective at inducing a protective immune response in goats. However, further research is needed to fully understand the immune response to combined vaccines.

Indexed as

Bacterial VaccinesGoat DiseasesGoatsPeste-des-Petits-RuminantsPleuropneumonia, ContagiousViral VaccinesAnimalsCapripoxvirusEthiopiaFemaleMalePeste-des-petits-ruminants virusPoxviridae InfectionsSheepSheep DiseasesBacterial VaccinesViral VaccinesEthiopiaGoatsImmunogenicityMultiple vaccinesSafety

Identifiers

PMID39308707
PMCPMC11415898

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.