Evidence map›Paper›PMID 39308606›Full record

ArticleRadiology case reports2024

First documented case of ichthyosis prematurity syndrome in Iraq: A case report with literature review.

Ahmed Dheyaa Al-Obaidi, Reem Al-Obiade, Sajjad Ghanim Al-Badri, Nabeel Al-Fatlawi, Mustafa Najah Al-Obaidi, Hashim Talib Hashim, Asma Al-Zeena, Mustafa Al-Musawi, Dima Sarah, Abdullah Al-Awad

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In one paragraph

Article in Radiology case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ahmed Dheyaa Al-ObaidiDepartment of Internal Medicine, University of Baghdad, College of Medicine, Baghdad, Iraq.
Reem Al-ObiadeDepartment of Internal Medicine, University of Baghdad, College of Medicine, Baghdad, Iraq.
Sajjad Ghanim Al-BadriDepartment of Internal Medicine, University of Baghdad, College of Medicine, Baghdad, Iraq.
Nabeel Al-FatlawiDepartment of Internal Medicine, University of Baghdad, College of Medicine, Baghdad, Iraq.
Mustafa Najah Al-ObaidiDepartment of Internal Medicine, University of Baghdad, College of Medicine, Baghdad, Iraq.
Hashim Talib HashimResearch Department, University of Warith Al-Anbiyaa, College of Medicine, Karbala, Iraq.
Asma Al-ZeenaPediatrics Department, University of Al-Mustansiriyah, College Of Medicine, Baghdad, Iraq.
Mustafa Al-MusawiDepartment of Internal Medicine, University of Baghdad, College of Medicine, Baghdad, Iraq.
Dima SarahDepartment of Internal Medicine, University of Baghdad, College of Medicine, Baghdad, Iraq.
Abdullah Al-AwadDepartment of Internal Medicine, University of Baghdad, College of Medicine, Baghdad, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ichthyosis Prematurity Syndrome (IPS) is a rare autosomal recessive disorder characterized by premature birth, respiratory distress, and distinctive skin abnormalities. Infants with IPS typically present between 30 and 34 weeks of gestation with a thick, caseous, desquamating epidermis resembling vernix caseosa. We report a case of a female neonate born at 30 weeks, weighing 1400 grams, with severe respiratory distress and characteristic skin abnormalities. Immediate intervention, including mechanical ventilation and surfactant therapy, was essential. Histopathological examination revealed hyperkeratosis, parakeratosis, and a thickened stratum corneum, with genetic testing confirming FATP4 gene mutations. Comprehensive care by a multidisciplinary team, including CPAP, emollients, and enteral feeding, led to significant improvement, and the neonate was discharged after 4 weeks. This is the first reported case of IPS in Iraq. This case highlights the importance of early recognition, genetic testing, and a coordinated care approach for managing IPS, emphasizing the need for awareness of its characteristic features to improve patient outcomes.

Indexed as

GeneticsIchthyosis prematurity syndromeIraqRespiratory distress syndromeSkin desquamation

Identifiers

PMID39308606
PMCPMC11416458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.