Evidence map›Paper›PMID 39308596›Full record

ArticleAmerican journal of clinical and experimental urology2024

Steps toward identification of a novel cue-positive overactive bladder phenotype in women with high-bother urinary urgency.

Sarah T Kodama, Ria Khandpur, Jared Dunlap, Julia Smolen, Chris Keshishian, Kathleen A O'Connell, Linda S Burkett, Lauren N Siff, John E Speich, Adam P Klausner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of clinical and experimental urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sarah T KodamaDepartment of Surgery/Division of Urology, Virginia Commonwealth University School of Medicine Richmond, VA, USA.
Ria KhandpurDepartment of Surgery/Division of Urology, Virginia Commonwealth University School of Medicine Richmond, VA, USA.
Jared DunlapDepartment of Surgery/Division of Urology, Virginia Commonwealth University School of Medicine Richmond, VA, USA.
Julia SmolenDepartment of Surgery/Division of Urology, Virginia Commonwealth University School of Medicine Richmond, VA, USA.
Chris KeshishianDepartment of Surgery/Division of Urology, Virginia Commonwealth University School of Medicine Richmond, VA, USA.
Kathleen A O'ConnellDepartment of Health and Behavior Studies, Columbia University New York, NY, USA.
Linda S BurkettDepartment of Obstetrics and Gynecology, Virginia Commonwealth University Richmond, VA, USA.
Lauren N SiffDepartment of Obstetrics and Gynecology, Virginia Commonwealth University Richmond, VA, USA.
John E SpeichDepartment of Mechanical and Nuclear Engineering of Engineering, College of Engineering, Virginia Commonwealth University Richmond, VA, USA.
Adam P KlausnerDepartment of Surgery/Division of Urology, Virginia Commonwealth University School of Medicine Richmond, VA, USA.

Funding

The Detrusor Tension Sensor: A Model for Novel Cystometrics in Overactive BladderR01DK101719 · NIDDK · VIRGINIA COMMONWEALTH UNIVERSITY · PI KLAUSNER, ADAM PHILIP, SPEICH, JOHN E · 2015 to 2023
$2.4M
NIDDK NIH HHS R01 DK101719
6 · The paper itself

Abstract

objectiveThe objective of this study was to investigate the relationship between situational cues (running water, stress, cold, etc.) and overactive bladder (OAB) symptoms.

methodsWomen scheduled for urodynamic studies for clinical indications completed surveys to characterize OAB (ICIQ-OAB and OAB-V3) and responses to situational cues (validated long-form cues survey and a novel short-form cues survey). Participants were divided into two groups (Low-Bother urgency vs. High-Bother urgency), and OAB and cue survey responses were compared.

resultsA total of 47 participants were enrolled in the study with 36 meeting inclusion criteria (15 Low-Bother and 21 High-Bother) with an overall mean age of 60.0 ± 10.0 years. The High-Bother urgency group scored significantly higher on multiple cue items in the long-form (P<0.05) and only "running water" in the short-form cues survey (P<0.05). In addition, "running water" was the only cue that was scored higher in both surveys (P<0.05).

conclusionsThis study showed that patients with High-Bother urgency may have increased symptom responses to environmental, mood, and cognitive cues. These findings suggest increased sensitivity to cues, especially "running water" in participants with bothersome OAB and the potential presence of a cue-specific OAB phenotype.

Indexed as

cueslower urinary tract symptomsOveractive bladderurinary urge incontinence

Identifiers

PMID39308596
PMCPMC11411182

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.