Evidence map›Paper›PMID 39308545›Full record

ArticleBioactive materials2024

Antimicrobial hydrogel foam dressing with controlled release of gallium maltolate for infection control in chronic wounds.

Ziyang Lan, Leopold Guo, Alan Fletcher, Nicolai Ang, Canaan Whitfield-Cargile, Laura Bryan, Shannara Welch, Lauren Richardson, Elizabeth Cosgriff-Hernandez

Abstract read
In one paragraph

Article in Bioactive materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Antimicrobial Hydrogel for Diabetic Wound Treatment.International journal of nanomedicine · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ziyang LanDepartment of Biomedical Engineering, the University of Texas at Austin, Austin, TX, 78712, USA.
Leopold GuoDepartment of Biomedical Engineering, the University of Texas at Austin, Austin, TX, 78712, USA.
Alan FletcherDepartment of Biomedical Engineering, the University of Texas at Austin, Austin, TX, 78712, USA.
Nicolai AngDepartment of Biomedical Engineering, the University of Texas at Austin, Austin, TX, 78712, USA.
Canaan Whitfield-CargileDepartment of Large Animal Medicine, University of Georgia, Athens, GA, 30602, USA.
Laura BryanDepartment of Pathobiology, Texas A&M University, College Station, TX, 77843, USA.
Shannara WelchClinical Microbiology Lab, Veterinary Teaching Hospital, Texas A&M University, College Station, TX, 77843, USA.
Lauren RichardsonDepartment of Large Animal Medicine, University of Georgia, Athens, GA, 30602, USA.
Elizabeth Cosgriff-HernandezDepartment of Biomedical Engineering, the University of Texas at Austin, Austin, TX, 78712, USA.

Funding

Antimicrobial Hydrogel Foam Dressings for Infected Chronic WoundsR21AR076107 · NIAMS · UNIVERSITY OF TEXAS AT AUSTIN · PI COSGRIFF-HERNANDEZ, ELIZABETH MARIE · 2020 to 2021
$367k
NIAMS NIH HHS R21 AR076107
6 · The paper itself

Abstract

Effective treatment of infection in chronic wounds is critical to improve patient outcomes and prevent severe complications, including systemic infections, increased morbidity, and amputations. Current treatments, including antibiotic administration and antimicrobial dressings, are challenged by the increasing prevalence of antibiotic resistance and patients' sensitivity to the delivered agents. Previous studies have demonstrated the potential of a new antimicrobial agent, Gallium maltolate (GaM); however, the high burst release from the GaM-loaded hydrogel gauze required frequent dressing changes. To address this need, we developed a hydrogel foam-based wound dressing with GaM-loaded microspheres for sustained infection control. First, the minimal inhibitory and bactericidal concentrations (MIC and MBC) of GaM against two

Indexed as

Antimicrobials wound dressingChronic woundsHydrogel foamInfection controlMicrosphere

Identifiers

PMID39308545
PMCPMC11415875

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.