Evidence map›Paper›PMID 39308241›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

A ROS-Responsive Lipid Nanoparticles Release Multifunctional Hydrogel Based on Microenvironment Regulation Promotes Infected Diabetic Wound Healing.

Hao Yang, Dongming Lv, Shanqiang Qu, Hailin Xu, Shuting Li, Zhiyong Wang, Xiaoling Cao, Yanchao Rong, Xiaohui Li, Honglin Wu and 4 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

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  16. NbAdvanced healthcare materials · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hao YangDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.ORCID 0000-0002-5388-5039
Dongming LvDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Shanqiang QuDepartment of Neurosurgery, Nanfang Hospital of Southern Medical University, Guangzhou, 510515, China.
Hailin XuDepartment of Dermatology, Dermatology Hospital of Southern Medical University, Guangzhou, 510091, China.
Shuting LiDepartment of Plastic Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Zhiyong WangDepartment of Joint Surgery, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Xiaoling CaoDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Yanchao RongDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Xiaohui LiDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Honglin WuDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Yongfei ChenDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Jiayuan ZhuDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Bing TangDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Zhicheng HuDepartment of Burn and Wound Repair, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.ORCID 0000-0002-0026-0676

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2024A1515010485National Natural Science Foundation of China 82072180National Natural Science Foundation of China 82072181National Natural Science Foundation of China 82172213
6 · The paper itself

Abstract

The continuous imbalance of the diabetic wound microenvironment is an important cause of chronic nonhealing, which manifests as a vicious cycle between excessive accumulation of reactive oxygen species (ROS) and abnormal healing. Regulating the microenvironment by suppressing wound inflammation, oxidative stress, and bacterial infection is a key challenge in treating diabetic wounds. In this study, ROS-responsive hydrogels are developed composed of silk fibroin methacrylated (SFMA), modified collagen type III (rCol

Indexed as

HydrogelsNanoparticlesReactive Oxygen SpeciesWound HealingAnimalsDiabetes Mellitus, ExperimentalDisease Models, AnimalLiposomesMiceRatsHydrogelsLipid NanoparticlesLiposomesReactive Oxygen Speciesantibacterialanti‐inflammationantioxidationdiabetic woundmultifunctional hydrogel

Identifiers

PMID39308241
PMCPMC11578374

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.