Evidence map›Paper›PMID 39308173›Full record

ArticlePsychiatric services (Washington, D.C.)2025

Characterizing Schizophrenia Spectrum Disorders: Results of the U.S. Mental and Substance Use Disorders Prevalence Study.

Natalie Bareis, Mark Edlund, Heather Ringeisen, Heidi Guyer, Lisa B Dixon, Mark Olfson, Thomas E Smith, Lydia Chwastiak, Maria Monroe-DeVita, Marvin Swartz and 5 more

Abstract read
In one paragraph

Article in Psychiatric services (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Natalie BareisDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Mark EdlundDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Heather RingeisenDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Heidi GuyerDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Lisa B DixonDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Mark OlfsonDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Thomas E SmithDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Lydia ChwastiakDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Maria Monroe-DeVitaDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Marvin SwartzDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Jeffrey SwansonDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Elizabeth Sinclair HancqDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Paul GeigerDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Noah T KreskiDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
T Scott StroupDepartment of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).

Funding

Machine Learning for Precision Treatments in SchizophreniaK23MH129628 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI BAREIS, NATALIE · 2022 to 2025
$782k
NIMH NIH HHS K23 MH129628NIMH NIH HHS L30 MH131131
6 · The paper itself

Abstract

objectiveCurrent information on treatment and clinical characteristics of U.S. adults with schizophrenia spectrum disorders (i.e., schizophrenia, schizoaffective, and schizophreniform disorders) may help inform public health policy and service development for this population.

methodsData were from the U.S. Mental and Substance Use Disorders Prevalence Study, conducted from October 2020 to October 2022. Clinicians administered the Structured Clinical Interview for the DSM-5 for past-year psychiatric and substance use disorder diagnoses among adults ages 18-65 years. Using sampling weights, the authors examined clinical and treatment characteristics among those with schizophrenia spectrum disorders and compared sociodemographic characteristics and comorbid behavioral health conditions of individuals with or without such disorders (N=4,764).

resultsAmong 114 adults with schizophrenia spectrum disorders, the most common comorbid conditions were major depressive episode (52%, 95% CI=34%-69%) and alcohol use (23%, CI=3%-43%), cannabis use (20%, 95% CI=1%-39%), and posttraumatic stress (17%, 95% CI=5%-30%) disorders. Global Assessment of Functioning scores were lower among people with than among those without schizophrenia spectrum disorders (mean±SE=44.8±2.0 vs. 77.2±0.5, p<0.01, respectively), indicating worse functioning. In the past year, 71% (95% CI=55%-87%) of adults with schizophrenia spectrum disorders received at least some mental health treatment, and 26% (95% CI=13%-38%) received minimally adequate treatment.

conclusionsIndividuals with schizophrenia spectrum disorders face substantial challenges in the United States, including high rates of comorbid mental health conditions and substance use; few received adequate treatment. A strong social safety net and active clinical interventions are required to address the socioeconomic challenges and unmet mental health service needs of this population.

Indexed as

ComorbidityPsychotic DisordersSchizophreniaSubstance-Related DisordersAdolescentAdultAgedFemaleHumansMajor Depressive DisorderMaleMiddle AgedPrevalenceUnited StatesYoung AdultAlcohol and drug abuseDrug treatmentEpidemiologyPsychopharmacologySchizophrenia

Identifiers

PMID39308173
PMCPMC11693490

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